TERT (telomerase reverse transcriptase)

Identity

Other names	EST2
	TCS1
	TP2
	TRT
	hEST2
HGNC	TERT
Location	5p15.33
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TERT   11730
Entrez_Gene	TERT  7015  telomerase reverse transcriptase
	Cards
GeneCards	TERT
Ensembl	TERT [Search_View]   ENSG00000164362 [Gene_View]
Genatlas	TERT
GeneLynx	TERT
eGenome	TERT
euGene	7015
	Genomic and cartography
GoldenPath	TERT  -  5p15.33   chr5:1306287-1348162 -  5p15.33   [Description]    (hg18-March_2006)
Ensembl	TERT - 5p15.33 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TERT
	Gene and transcription
Genbank	AB085628 [ ENTREZ ]
Genbank	AB086379 [ ENTREZ ]
Genbank	AB086950 [ ENTREZ ]
Genbank	AF015950 [ ENTREZ ]
Genbank	AF018167 [ ENTREZ ]
RefSeq	NM_198253 [ SRS ]    NM_198253 [ ENTREZ ]
RefSeq	NM_198255 [ SRS ]    NM_198255 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_006576 [ SRS ]    NT_006576 [ ENTREZ ]
RefSeq	NW_001838923 [ SRS ]    NW_001838923 [ ENTREZ ]
RefSeq	NW_922518 [ SRS ]    NW_922518 [ ENTREZ ]
AceView	TERT AceView - NCBI
Unigene	Hs.492203 [ SRS ]    Hs.492203 [ NCBI ]     HS492203 [ spliceNest ]
Fast-db	1029 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O14746 [ SRS]    O14746 [ EXPASY ]     O14746 [ INTERPRO ]     O14746 [ UNIPROT ]
Prosite	PS50878 RT_POL [ SRS ]    PS50878 RT_POL [ Expasy ]
Interpro	IPR000477 DNA_pol_RVTase [ SRS ]    IPR000477 DNA_pol_RVTase [ EBI ]
Interpro	IPR003545 Telomerase_RT [ SRS ]    IPR003545 Telomerase_RT [ EBI ]
CluSTr	O14746
Blocks	O14746
PDB	2BCK [ SRS ]    2BCK [ PdbSum ],   2BCK [ IMB ]   2BCK [ RSDB ]
HPRD	01754
	Protein Interaction databases
DIP	O14746
IntAct	O14746
	Polymorphism : SNP, mutations, diseases
OMIM	127550;178500;187270;609135    [ map ]
GENECLINICS	127550;178500;187270;609135
SNP	TERT [dbSNP-NCBI]
SNP	NM_198253 [SNP-NCI]
SNP	NM_198255 [SNP-NCI]
SNP	TERT [GeneSNPs - Utah]  TERT] [HGBASE - SRS]
HAPMAP	TERT [HAPMAP]
COSMIC	TERT [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TERT
	General knowledge
Family Browser	TERT [UCSC Family Browser]
SOURCE	NM_198253
SOURCE	NM_198255
SMD	Hs.492203
SAGE	Hs.492203
Enzyme	2.7.7.49 [ Enzyme-Expasy ]   2.7.7.49 [ Enzyme-SRS ]   2.7.7.49 [ IntEnz-EBI ]   2.7.7.49 [ BRENDA ]   2.7.7.49 [ KEGG ]   2.7.7.49 [ WIT ]
GO	telomere maintenance [Amigo]  telomere maintenance
GO	chromosome, telomeric region [Amigo]  chromosome, telomeric region
GO	DNA binding [Amigo]  DNA binding
GO	telomeric template RNA reverse transcriptase activity [Amigo]  telomeric template RNA reverse transcriptase activity
GO	RNA binding [Amigo]  RNA binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	chromosome [Amigo]  chromosome
GO	telomerase holoenzyme complex [Amigo]  telomerase holoenzyme complex
GO	RNA-dependent DNA replication [Amigo]  RNA-dependent DNA replication
GO	transferase activity [Amigo]  transferase activity
GO	nucleotidyltransferase activity [Amigo]  nucleotidyltransferase activity
GO	telomeric DNA binding [Amigo]  telomeric DNA binding
BIOCARTA	Role of nicotinic acetylcholine receptors in the regulation of apoptosis    [Genes]
BIOCARTA	Telomeres, Telomerase, Cellular Aging, and Immortality    [Genes]
PubGene	TERT
TreeFam	TERT
CTD	7015 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TERT Related clones (RZPD - Berlin)
	PubMed
PubMed	415 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:34:41 2008