THBD (thrombomodulin)

Identity

Other names	CD141
	THRM
	TM
HGNC	THBD
Location	20p11.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	THBD   11784
Entrez_Gene	THBD  7056  thrombomodulin
	Cards
GeneCards	THBD
Ensembl	THBD [Search_View]   ENSG00000178726 [Gene_View]
Genatlas	THBD
GeneLynx	THBD
eGenome	THBD
euGene	7056
	Genomic and cartography
GoldenPath	THBD  -  20p11.2   chr20:22974270-22978301 -  20p11.21   [Description]    (hg18-March_2006)
Ensembl	THBD - 20p11.21 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	THBD
	Gene and transcription
Genbank	AI285986 [ ENTREZ ]
Genbank	AK091934 [ ENTREZ ]
Genbank	AK123557 [ ENTREZ ]
Genbank	BC035602 [ ENTREZ ]
Genbank	BC053357 [ ENTREZ ]
RefSeq	NM_000361 [ SRS ]    NM_000361 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_001838653 [ SRS ]    NW_001838653 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
AceView	THBD AceView - NCBI
Unigene	Hs.2030 [ SRS ]    Hs.2030 [ NCBI ]     HS2030 [ spliceNest ]
Fast-db	6776 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P07204 [ SRS]    P07204 [ EXPASY ]     P07204 [ INTERPRO ]     P07204 [ UNIPROT ]
Prosite	PS00010 ASX_HYDROXYL [ SRS ]    PS00010 ASX_HYDROXYL [ Expasy ]
Prosite	PS50041 C_TYPE_LECTIN_2 [ SRS ]    PS50041 C_TYPE_LECTIN_2 [ Expasy ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Prosite	PS01187 EGF_CA [ SRS ]    PS01187 EGF_CA [ Expasy ]
Interpro	IPR001304 C-type_lectin [ SRS ]    IPR001304 C-type_lectin [ EBI ]
Interpro	IPR016186 C-type_lectin-like [ SRS ]    IPR016186 C-type_lectin-like [ EBI ]
Interpro	IPR016316 CD93/CD141 [ SRS ]    IPR016316 CD93/CD141 [ EBI ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR000152 EGF-type_Asp/Asn_hydroxyl_CS [ SRS ]    IPR000152 EGF-type_Asp/Asn_hydroxyl_CS [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR001881 EGF_Ca_bd [ SRS ]    IPR001881 EGF_Ca_bd [ EBI ]
Interpro	IPR013091 EGF_Ca_bd_2 [ SRS ]    IPR013091 EGF_Ca_bd_2 [ EBI ]
Interpro	IPR006209 EGF_like [ SRS ]    IPR006209 EGF_like [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR001491 Thrombomodulin [ SRS ]    IPR001491 Thrombomodulin [ EBI ]
Interpro	IPR015149 Tme5_EGF_like [ SRS ]    IPR015149 Tme5_EGF_like [ EBI ]
CluSTr	P07204
Pfam	PF00008 EGF [ SRS ]    PF00008 EGF [ Sanger ]    pfam00008 [ NCBI-CDD ]
Pfam	PF07645 EGF_CA [ SRS ]    PF07645 EGF_CA [ Sanger ]    pfam07645 [ NCBI-CDD ]
Pfam	PF00059 Lectin_C [ SRS ]    PF00059 Lectin_C [ Sanger ]    pfam00059 [ NCBI-CDD ]
Pfam	PF09064 Tme5_EGF_like [ SRS ]    PF09064 Tme5_EGF_like [ Sanger ]    pfam09064 [ NCBI-CDD ]
Smart	SM00034 CLECT [EMBL]
Smart	SM00181 EGF [EMBL]
Smart	SM00179 EGF_CA [EMBL]
Blocks	P07204
PDB	1ADX [ SRS ]    1ADX [ PdbSum ],   1ADX [ IMB ]   1ADX [ RSDB ]
PDB	1DQB [ SRS ]    1DQB [ PdbSum ],   1DQB [ IMB ]   1DQB [ RSDB ]
PDB	1DX5 [ SRS ]    1DX5 [ PdbSum ],   1DX5 [ IMB ]   1DX5 [ RSDB ]
PDB	1EGT [ SRS ]    1EGT [ PdbSum ],   1EGT [ IMB ]   1EGT [ RSDB ]
PDB	1FGD [ SRS ]    1FGD [ PdbSum ],   1FGD [ IMB ]   1FGD [ RSDB ]
PDB	1FGE [ SRS ]    1FGE [ PdbSum ],   1FGE [ IMB ]   1FGE [ RSDB ]
PDB	1HLT [ SRS ]    1HLT [ PdbSum ],   1HLT [ IMB ]   1HLT [ RSDB ]
PDB	1TMR [ SRS ]    1TMR [ PdbSum ],   1TMR [ IMB ]   1TMR [ RSDB ]
PDB	1ZAQ [ SRS ]    1ZAQ [ PdbSum ],   1ZAQ [ IMB ]   1ZAQ [ RSDB ]
PDB	2ADX [ SRS ]    2ADX [ PdbSum ],   2ADX [ IMB ]   2ADX [ RSDB ]
HPRD	01764
	Protein Interaction databases
DIP	P07204
IntAct	P07204
	Polymorphism : SNP, mutations, diseases
OMIM	188040    [ map ]
GENECLINICS	188040
SNP	THBD [dbSNP-NCBI]
SNP	NM_000361 [SNP-NCI]
SNP	THBD [GeneSNPs - Utah]  THBD] [HGBASE - SRS]
HAPMAP	THBD [HAPMAP]
HGMD	THBD
	General knowledge
Family Browser	THBD [UCSC Family Browser]
SOURCE	NM_000361
SMD	Hs.2030
SAGE	Hs.2030
GO	transmembrane receptor activity [Amigo]  transmembrane receptor activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	protein binding [Amigo]  protein binding
GO	extracellular space [Amigo]  extracellular space
GO	plasma membrane [Amigo]  plasma membrane
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	female pregnancy [Amigo]  female pregnancy
GO	blood coagulation [Amigo]  blood coagulation
GO	embryonic development [Amigo]  embryonic development
GO	response to X-ray [Amigo]  response to X-ray
GO	response to lipopolysaccharide [Amigo]  response to lipopolysaccharide
GO	response to cAMP [Amigo]  response to cAMP
KEGG	Complement and coagulation cascades
PubGene	THBD
TreeFam	THBD
CTD	7056 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	THBD Related clones (RZPD - Berlin)
	PubMed
PubMed	114 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:34:56 2008