TJP1 (tight junction protein 1 (zona occludens 1))

Identity

Other names	DKFZp686M05161
	MGC133289
	ZO-1
Hugo	TJP1
Location	15q13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	TJP1
GDB	TJP1
Entrez_Gene	TJP1  7082  tight junction protein 1 (zona occludens 1)
	Cards
GeneCards	TJP1
Ensembl	TJP1 [Search_View]   ENSG00000136352 [Gene_View]
Genatlas	TJP1
GeneLynx	TJP1
eGenome	TJP1
euGene	7082
	Genomic and cartography
GoldenPath	TJP1  -  15q13   chr15:27779651-27901998 -  15q13.1   [Description]    (hg18-March_2006)
Ensembl	TJP1 - 15q13.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TJP1
	Gene and transcription
Genbank	AB370197 [ ENTREZ ]
Genbank	AF035298 [ ENTREZ ]
Genbank	BC036090 [ ENTREZ ]
Genbank	BC111712 [ ENTREZ ]
Genbank	BX640879 [ ENTREZ ]
RefSeq	NM_003257 [ SRS ]    NM_003257 [ ENTREZ ]
RefSeq	NM_175610 [ SRS ]    NM_175610 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_925796 [ SRS ]    NW_925796 [ ENTREZ ]
AceView	TJP1 AceView - NCBI
Unigene	Hs.510833 [ SRS ]    Hs.510833 [ NCBI ]     HS510833 [ spliceNest ]
Fast-db	911 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q07157 [ SRS]    Q07157 [ EXPASY ]     Q07157 [ INTERPRO ]
Prosite	PS00856 GUANYLATE_KINASE_1 [ SRS ]    PS00856 GUANYLATE_KINASE_1 [ Expasy ]
Prosite	PS50052 GUANYLATE_KINASE_2 [ SRS ]    PS50052 GUANYLATE_KINASE_2 [ Expasy ]
Prosite	PS50106 PDZ [ SRS ]    PS50106 PDZ [ Expasy ]
Prosite	PS50002 SH3 [ SRS ]    PS50002 SH3 [ Expasy ]
Prosite	PS51145 ZU5 [ SRS ]    PS51145 ZU5 [ Expasy ]
Interpro	IPR008144 Guanylate_kin [ SRS ]    IPR008144 Guanylate_kin [ EBI ]
Interpro	IPR008145 Guanylt/Ca [ SRS ]    IPR008145 Guanylt/Ca [ EBI ]
Interpro	IPR001478 PDZ [ SRS ]    IPR001478 PDZ [ EBI ]
Interpro	IPR001452 SH3 [ SRS ]    IPR001452 SH3 [ EBI ]
Interpro	IPR011511 SH3_2 [ SRS ]    IPR011511 SH3_2 [ EBI ]
Interpro	IPR005417 ZonOcculdens [ SRS ]    IPR005417 ZonOcculdens [ EBI ]
Interpro	IPR005418 ZonOcculS1 [ SRS ]    IPR005418 ZonOcculS1 [ EBI ]
Interpro	IPR000906 ZU5 [ SRS ]    IPR000906 ZU5 [ EBI ]
CluSTr	Q07157
Pfam	PF00625 Guanylate_kin [ SRS ]    PF00625 Guanylate_kin [ Sanger ]    pfam00625 [ NCBI-CDD ]
Pfam	PF00595 PDZ [ SRS ]    PF00595 PDZ [ Sanger ]    pfam00595 [ NCBI-CDD ]
Pfam	PF07653 SH3_2 [ SRS ]    PF07653 SH3_2 [ Sanger ]    pfam07653 [ NCBI-CDD ]
Pfam	PF00791 ZU5 [ SRS ]    PF00791 ZU5 [ Sanger ]    pfam00791 [ NCBI-CDD ]
Smart	SM00072 GuKc [EMBL]
Smart	SM00228 PDZ [EMBL]
Smart	SM00326 SH3 [EMBL]
Smart	SM00218 ZU5 [EMBL]
Blocks	Q07157
PDB	2H2B [ SRS ]    2H2B [ PdbSum ],   2H2B [ IMB ]   2H2B [ RSDB ]
PDB	2H2C [ SRS ]    2H2C [ PdbSum ],   2H2C [ IMB ]   2H2C [ RSDB ]
PDB	2H3M [ SRS ]    2H3M [ PdbSum ],   2H3M [ IMB ]   2H3M [ RSDB ]
PDB	2JWE [ SRS ]    2JWE [ PdbSum ],   2JWE [ IMB ]   2JWE [ RSDB ]
PDB	2RCZ [ SRS ]    2RCZ [ PdbSum ],   2RCZ [ IMB ]   2RCZ [ RSDB ]
HPRD	03002
	Protein Interaction databases
DIP	Q07157
IntAct	Q07157
	Polymorphism : SNP, mutations, diseases
OMIM	601009    [ map ]
GENECLINICS	601009
SNP	TJP1 [dbSNP-NCBI]
SNP	NM_003257 [SNP-NCI]
SNP	NM_175610 [SNP-NCI]
SNP	TJP1 [GeneSNPs - Utah]  TJP1] [HGBASE - SRS]
HAPMAP	TJP1 [HAPMAP]
HGMD	TJP1
	General knowledge
Family Browser	TJP1 [UCSC Family Browser]
SOURCE	NM_003257
SOURCE	NM_175610
SMD	Hs.510833
SAGE	Hs.510833
GO	protein binding [Amigo]  protein binding
GO	protein binding [Amigo]  protein binding
GO	membrane fraction [Amigo]  membrane fraction
GO	plasma membrane [Amigo]  plasma membrane
GO	septate junction [Amigo]  septate junction
GO	tight junction [Amigo]  tight junction
GO	tight junction [Amigo]  tight junction
GO	intercellular junction assembly [Amigo]  intercellular junction assembly
GO	basolateral plasma membrane [Amigo]  basolateral plasma membrane
GO	cell junction [Amigo]  cell junction
KEGG	Adherens junction
KEGG	Tight junction
KEGG	Gap junction
KEGG	Epithelial cell signaling in Helicobacter pylori infection
PubGene	TJP1
TreeFam	TJP1
CTD	7082 [Comparative Genomics Database]
	Other databases
	Probes
Probe	TJP1 Related clones (RZPD - Berlin)
	PubMed
PubMed	76 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:32:05 2008