TLR1 (toll-like receptor 1)

Identity

Other names	CD281
	DKFZp547I0610
	DKFZp564I0682
	KIAA0012
	MGC104956
	MGC126311
	MGC126312
	TIL
	rsc786
Hugo	TLR1
Location	4p14
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	TLR1
GDB	TLR1
Entrez_Gene	TLR1  7096  toll-like receptor 1
	Cards
GeneCards	TLR1
Ensembl	TLR1 [Search_View]   ENSG00000174125 [Gene_View]
Genatlas	TLR1
GeneLynx	TLR1
eGenome	TLR1
euGene	7096
	Genomic and cartography
GoldenPath	TLR1  -  4p14   chr4:38474272-38482807 -  4p14   [Description]    (hg18-March_2006)
Ensembl	TLR1 - 4p14 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TLR1
	Gene and transcription
Genbank	AK292982 [ ENTREZ ]
Genbank	AL050262 [ ENTREZ ]
Genbank	AW408740 [ ENTREZ ]
Genbank	BC089403 [ ENTREZ ]
Genbank	BC109093 [ ENTREZ ]
RefSeq	NM_003263 [ SRS ]    NM_003263 [ ENTREZ ]
RefSeq	NC_000004 [ SRS ]    NC_000004 [ ENTREZ ]
RefSeq	NT_016297 [ SRS ]    NT_016297 [ ENTREZ ]
RefSeq	NW_925243 [ SRS ]    NW_925243 [ ENTREZ ]
AceView	TLR1 AceView - NCBI
Unigene	Hs.654532 [ SRS ]    Hs.654532 [ NCBI ]     HS654532 [ spliceNest ]
Fast-db	3391 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q15399 [ SRS]    Q15399 [ EXPASY ]     Q15399 [ INTERPRO ]
Prosite	PS50104 TIR [ SRS ]    PS50104 TIR [ Expasy ]
Interpro	IPR004075 IL1_rcpt_1 [ SRS ]    IPR004075 IL1_rcpt_1 [ EBI ]
Interpro	IPR001611 LRR [ SRS ]    IPR001611 LRR [ EBI ]
Interpro	IPR000483 LRR_C [ SRS ]    IPR000483 LRR_C [ EBI ]
Interpro	IPR000157 TIR [ SRS ]    IPR000157 TIR [ EBI ]
CluSTr	Q15399
Pfam	PF00560 LRR_1 [ SRS ]    PF00560 LRR_1 [ Sanger ]    pfam00560 [ NCBI-CDD ]
Pfam	PF01463 LRRCT [ SRS ]    PF01463 LRRCT [ Sanger ]    pfam01463 [ NCBI-CDD ]
Pfam	PF01582 TIR [ SRS ]    PF01582 TIR [ Sanger ]    pfam01582 [ NCBI-CDD ]
Smart	SM00082 LRRCT [EMBL]
Smart	SM00255 TIR [EMBL]
Blocks	Q15399
PDB	1FYV [ SRS ]    1FYV [ PdbSum ],   1FYV [ IMB ]   1FYV [ RSDB ]
HPRD	03119
	Protein Interaction databases
DIP	Q15399
IntAct	Q15399
	Polymorphism : SNP, mutations, diseases
OMIM	601194    [ map ]
GENECLINICS	601194
SNP	TLR1 [dbSNP-NCBI]
SNP	NM_003263 [SNP-NCI]
SNP	TLR1 [GeneSNPs - Utah]  TLR1] [HGBASE - SRS]
HAPMAP	TLR1 [HAPMAP]
HGMD	TLR1
	General knowledge
Family Browser	TLR1 [UCSC Family Browser]
SOURCE	NM_003263
SMD	Hs.654532
SAGE	Hs.654532
GO	transmembrane receptor activity [Amigo]  transmembrane receptor activity
GO	protein binding [Amigo]  protein binding
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	inflammatory response [Amigo]  inflammatory response
GO	signal transduction [Amigo]  signal transduction
GO	cytoplasmic vesicle [Amigo]  cytoplasmic vesicle
GO	macrophage activation [Amigo]  macrophage activation
GO	positive regulation of tumor necrosis factor biosynthetic process [Amigo]  positive regulation of tumor necrosis factor biosynthetic process
GO	innate immune response [Amigo]  innate immune response
GO	positive regulation of interleukin-6 biosynthetic process [Amigo]  positive regulation of interleukin-6 biosynthetic process
BIOCARTA	Toll-Like Receptor Pathway    [Genes]
KEGG	Toll-like receptor signaling pathway
PubGene	TLR1
TreeFam	TLR1
CTD	7096 [Comparative Genomics Database]
	Other databases
	Probes
Probe	TLR1 Related clones (RZPD - Berlin)
	PubMed
PubMed	41 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:32:09 2008