TLR6 (toll-like receptor 6)

Identity

Other names	CD286
Hugo	TLR6
Location	4p14
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	TLR6
GDB	TLR6
Entrez_Gene	TLR6  10333  toll-like receptor 6
	Cards
GeneCards	TLR6
Ensembl	TLR6 [Search_View]   ENSG00000174130 [Gene_View]
Genatlas	TLR6
GeneLynx	TLR6
eGenome	TLR6
euGene	10333
	Genomic and cartography
GoldenPath	TLR6  -  4p14   chr4:38504803-38507555 -  4p14   [Description]    (hg18-March_2006)
Ensembl	TLR6 - 4p14 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TLR6
	Gene and transcription
Genbank	AB020807 [ ENTREZ ]
Genbank	BC111755 [ ENTREZ ]
RefSeq	NM_006068 [ SRS ]    NM_006068 [ ENTREZ ]
RefSeq	AC_000047 [ SRS ]    AC_000047 [ ENTREZ ]
RefSeq	NC_000004 [ SRS ]    NC_000004 [ ENTREZ ]
RefSeq	NT_016297 [ SRS ]    NT_016297 [ ENTREZ ]
RefSeq	NW_922073 [ SRS ]    NW_922073 [ ENTREZ ]
AceView	TLR6 AceView - NCBI
Unigene	Hs.662185 [ SRS ]    Hs.662185 [ NCBI ]     HS662185 [ spliceNest ]
Fast-db	3394 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9Y2C9 [ SRS]    Q9Y2C9 [ EXPASY ]     Q9Y2C9 [ INTERPRO ]
Prosite	PS50104 TIR [ SRS ]    PS50104 TIR [ Expasy ]
Interpro	IPR004075 IL1_rcpt_1 [ SRS ]    IPR004075 IL1_rcpt_1 [ EBI ]
Interpro	IPR001611 LRR [ SRS ]    IPR001611 LRR [ EBI ]
Interpro	IPR000483 LRR_C [ SRS ]    IPR000483 LRR_C [ EBI ]
Interpro	IPR000157 TIR [ SRS ]    IPR000157 TIR [ EBI ]
CluSTr	Q9Y2C9
Pfam	PF00560 LRR_1 [ SRS ]    PF00560 LRR_1 [ Sanger ]    pfam00560 [ NCBI-CDD ]
Pfam	PF01463 LRRCT [ SRS ]    PF01463 LRRCT [ Sanger ]    pfam01463 [ NCBI-CDD ]
Pfam	PF01582 TIR [ SRS ]    PF01582 TIR [ Sanger ]    pfam01582 [ NCBI-CDD ]
Smart	SM00082 LRRCT [EMBL]
Smart	SM00255 TIR [EMBL]
Blocks	Q9Y2C9
HPRD	05656
	Protein Interaction databases
DIP	Q9Y2C9
IntAct	Q9Y2C9
	Polymorphism : SNP, mutations, diseases
OMIM	605403    [ map ]
GENECLINICS	605403
SNP	TLR6 [dbSNP-NCBI]
SNP	NM_006068 [SNP-NCI]
SNP	TLR6 [GeneSNPs - Utah]  TLR6] [HGBASE - SRS]
HAPMAP	TLR6 [HAPMAP]
HGMD	TLR6
	General knowledge
Family Browser	TLR6 [UCSC Family Browser]
SOURCE	NM_006068
SMD	Hs.662185
SAGE	Hs.662185
GO	transmembrane receptor activity [Amigo]  transmembrane receptor activity
GO	protein binding [Amigo]  protein binding
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	inflammatory response [Amigo]  inflammatory response
GO	signal transduction [Amigo]  signal transduction
GO	signal transduction [Amigo]  signal transduction
GO	activation of NF-kappaB-inducing kinase [Amigo]  activation of NF-kappaB-inducing kinase
GO	lipoprotein binding [Amigo]  lipoprotein binding
GO	intrinsic to membrane [Amigo]  intrinsic to membrane
GO	cytoplasmic vesicle [Amigo]  cytoplasmic vesicle
GO	T-helper 1 type immune response [Amigo]  T-helper 1 type immune response
GO	defense response to bacterium [Amigo]  defense response to bacterium
GO	positive regulation of I-kappaB kinase/NF-kappaB cascade [Amigo]  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO	positive regulation of JNK activity [Amigo]  positive regulation of JNK activity
GO	innate immune response [Amigo]  innate immune response
GO	positive regulation of interleukin-6 biosynthetic process [Amigo]  positive regulation of interleukin-6 biosynthetic process
KEGG	Toll-like receptor signaling pathway
PubGene	TLR6
TreeFam	TLR6
CTD	10333 [Comparative Genomics Database]
	Other databases
	Probes
Probe	TLR6 Related clones (RZPD - Berlin)
	PubMed
PubMed	27 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:32:11 2008