TLR7 (toll-like receptor 7)

Identity

Other names	-
Hugo	TLR7
Location	Xp22.3
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	TLR7
GDB	TLR7
Entrez_Gene	TLR7  51284  toll-like receptor 7
	Cards
GeneCards	TLR7
Ensembl	TLR7 [Search_View]   ENSG00000196664 [Gene_View]
Genatlas	TLR7
GeneLynx	TLR7
eGenome	TLR7
euGene	51284
	Genomic and cartography
GoldenPath	TLR7  -  Xp22.3   chrX:12795123-12818400 +  Xp22.2   [Description]    (hg18-March_2006)
Ensembl	TLR7 - Xp22.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TLR7
	Gene and transcription
Genbank	AF240467 [ ENTREZ ]
Genbank	AF245702 [ ENTREZ ]
Genbank	AY358292 [ ENTREZ ]
Genbank	BC033651 [ ENTREZ ]
Genbank	DQ891269 [ ENTREZ ]
RefSeq	NM_016562 [ SRS ]    NM_016562 [ ENTREZ ]
RefSeq	AC_000066 [ SRS ]    AC_000066 [ ENTREZ ]
RefSeq	NC_000023 [ SRS ]    NC_000023 [ ENTREZ ]
RefSeq	NT_011757 [ SRS ]    NT_011757 [ ENTREZ ]
RefSeq	NW_927700 [ SRS ]    NW_927700 [ ENTREZ ]
AceView	TLR7 AceView - NCBI
Unigene	Hs.659215 [ SRS ]    Hs.659215 [ NCBI ]     HS659215 [ spliceNest ]
Fast-db	1902 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9NYK1 [ SRS]    Q9NYK1 [ EXPASY ]     Q9NYK1 [ INTERPRO ]
Prosite	PS50104 TIR [ SRS ]    PS50104 TIR [ Expasy ]
Interpro	IPR004075 IL1_rcpt_1 [ SRS ]    IPR004075 IL1_rcpt_1 [ EBI ]
Interpro	IPR001611 LRR [ SRS ]    IPR001611 LRR [ EBI ]
Interpro	IPR000483 LRR_C [ SRS ]    IPR000483 LRR_C [ EBI ]
Interpro	IPR000372 LRR_cys_N [ SRS ]    IPR000372 LRR_cys_N [ EBI ]
Interpro	IPR003591 LRR_sub-typ [ SRS ]    IPR003591 LRR_sub-typ [ EBI ]
Interpro	IPR015765 LRR_Toll-like_rcpt7 [ SRS ]    IPR015765 LRR_Toll-like_rcpt7 [ EBI ]
Interpro	IPR000157 TIR [ SRS ]    IPR000157 TIR [ EBI ]
CluSTr	Q9NYK1
Pfam	PF00560 LRR_1 [ SRS ]    PF00560 LRR_1 [ Sanger ]    pfam00560 [ NCBI-CDD ]
Pfam	PF01463 LRRCT [ SRS ]    PF01463 LRRCT [ Sanger ]    pfam01463 [ NCBI-CDD ]
Pfam	PF01582 TIR [ SRS ]    PF01582 TIR [ Sanger ]    pfam01582 [ NCBI-CDD ]
Smart	SM00369 LRR_TYP [EMBL]
Smart	SM00082 LRRCT [EMBL]
Smart	SM00013 LRRNT [EMBL]
Blocks	Q9NYK1
HPRD	02295
	Protein Interaction databases
DIP	Q9NYK1
IntAct	Q9NYK1
	Polymorphism : SNP, mutations, diseases
OMIM	300365    [ map ]
GENECLINICS	300365
SNP	TLR7 [dbSNP-NCBI]
SNP	NM_016562 [SNP-NCI]
SNP	TLR7 [GeneSNPs - Utah]  TLR7] [HGBASE - SRS]
HAPMAP	TLR7 [HAPMAP]
COSMIC	TLR7 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TLR7
	General knowledge
Family Browser	TLR7 [UCSC Family Browser]
SOURCE	NM_016562
SMD	Hs.659215
SAGE	Hs.659215
GO	double-stranded RNA binding [Amigo]  double-stranded RNA binding
GO	single-stranded RNA binding [Amigo]  single-stranded RNA binding
GO	transmembrane receptor activity [Amigo]  transmembrane receptor activity
GO	protein binding [Amigo]  protein binding
GO	inflammatory response [Amigo]  inflammatory response
GO	signal transduction [Amigo]  signal transduction
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	siRNA binding [Amigo]  siRNA binding
GO	positive regulation of interferon-gamma biosynthetic process [Amigo]  positive regulation of interferon-gamma biosynthetic process
GO	innate immune response [Amigo]  innate immune response
GO	positive regulation of interferon-alpha biosynthetic process [Amigo]  positive regulation of interferon-alpha biosynthetic process
GO	positive regulation of interferon-beta biosynthetic process [Amigo]  positive regulation of interferon-beta biosynthetic process
GO	positive regulation of interleukin-8 biosynthetic process [Amigo]  positive regulation of interleukin-8 biosynthetic process
GO	defense response to virus [Amigo]  defense response to virus
BIOCARTA	Dendritic cells in regulating TH1 and TH2 Development    [Genes]
BIOCARTA	Toll-Like Receptor Pathway    [Genes]
KEGG	Toll-like receptor signaling pathway
PubGene	TLR7
TreeFam	TLR7
CTD	51284 [Comparative Genomics Database]
	Other databases
	Probes
Probe	TLR7 Related clones (RZPD - Berlin)
	PubMed
PubMed	36 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:32:11 2008