TNFRSF1A (tumor necrosis factor receptor superfamily, member 1A)

Identity

Other names	CD120a
	FPF
	MGC19588
	TBP1
	TNF-R
	TNF-R-I
	TNF-R55
	TNFAR
	TNFR1
	TNFR55
	TNFR60
	p55
	p55-R
	p60
HGNC	TNFRSF1A
Location	12p13.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TNFRSF1A   11916
Entrez_Gene	TNFRSF1A  7132  tumor necrosis factor receptor superfamily, member 1A
	Cards
GeneCards	TNFRSF1A
Ensembl	TNFRSF1A [Search_View]   ENSG00000067182 [Gene_View]
Genatlas	TNFRSF1A
GeneLynx	TNFRSF1A
eGenome	TNFRSF1A
euGene	7132
	Genomic and cartography
GoldenPath	TNFRSF1A  -  12p13.2   chr12:6308184-6321522 -  12p13.31   [Description]    (hg18-March_2006)
Ensembl	TNFRSF1A - 12p13.31 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TNFRSF1A
	Gene and transcription
Genbank	A21522 [ ENTREZ ]
Genbank	AK056611 [ ENTREZ ]
Genbank	AK291088 [ ENTREZ ]
Genbank	AK298729 [ ENTREZ ]
Genbank	AK304517 [ ENTREZ ]
RefSeq	NM_001065 [ SRS ]    NM_001065 [ ENTREZ ]
RefSeq	AC_000055 [ SRS ]    AC_000055 [ ENTREZ ]
RefSeq	AC_000144 [ SRS ]    AC_000144 [ ENTREZ ]
RefSeq	NC_000012 [ SRS ]    NC_000012 [ ENTREZ ]
RefSeq	NG_007506 [ SRS ]    NG_007506 [ ENTREZ ]
RefSeq	NT_009759 [ SRS ]    NT_009759 [ ENTREZ ]
RefSeq	NW_001838050 [ SRS ]    NW_001838050 [ ENTREZ ]
RefSeq	NW_925295 [ SRS ]    NW_925295 [ ENTREZ ]
AceView	TNFRSF1A AceView - NCBI
Unigene	Hs.713833 [ SRS ]    Hs.713833 [ NCBI ]     HS713833 [ spliceNest ]
Fast-db	939 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P19438 [ SRS]    P19438 [ EXPASY ]     P19438 [ INTERPRO ]     P19438 [ UNIPROT ]
Prosite	PS50017 DEATH_DOMAIN [ SRS ]    PS50017 DEATH_DOMAIN [ Expasy ]
Prosite	PS00652 TNFR_NGFR_1 [ SRS ]    PS00652 TNFR_NGFR_1 [ Expasy ]
Prosite	PS50050 TNFR_NGFR_2 [ SRS ]    PS50050 TNFR_NGFR_2 [ Expasy ]
Interpro	IPR000488 Death [ SRS ]    IPR000488 Death [ EBI ]
Interpro	IPR011029 DEATH_like [ SRS ]    IPR011029 DEATH_like [ EBI ]
Interpro	IPR001368 TNFR_c6 [ SRS ]    IPR001368 TNFR_c6 [ EBI ]
CluSTr	P19438
Pfam	PF00531 Death [ SRS ]    PF00531 Death [ Sanger ]    pfam00531 [ NCBI-CDD ]
Pfam	PF00020 TNFR_c6 [ SRS ]    PF00020 TNFR_c6 [ Sanger ]    pfam00020 [ NCBI-CDD ]
Smart	SM00005 DEATH [EMBL]
Smart	SM00208 TNFR [EMBL]
Blocks	P19438
PDB	1EXT [ SRS ]    1EXT [ PdbSum ],   1EXT [ IMB ]   1EXT [ RSDB ]
PDB	1FT4 [ SRS ]    1FT4 [ PdbSum ],   1FT4 [ IMB ]   1FT4 [ RSDB ]
PDB	1ICH [ SRS ]    1ICH [ PdbSum ],   1ICH [ IMB ]   1ICH [ RSDB ]
PDB	1NCF [ SRS ]    1NCF [ PdbSum ],   1NCF [ IMB ]   1NCF [ RSDB ]
PDB	1TNR [ SRS ]    1TNR [ PdbSum ],   1TNR [ IMB ]   1TNR [ RSDB ]
HPRD	01861
	Protein Interaction databases
DIP	P19438
IntAct	P19438
	Polymorphism : SNP, mutations, diseases
OMIM	142680;191190    [ map ]
GENECLINICS	142680;191190
SNP	TNFRSF1A [dbSNP-NCBI]
SNP	NM_001065 [SNP-NCI]
SNP	TNFRSF1A [GeneSNPs - Utah]  TNFRSF1A] [HGBASE - SRS]
HAPMAP	TNFRSF1A [HAPMAP]
COSMIC	TNFRSF1A [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TNFRSF1A
	General knowledge
Family Browser	TNFRSF1A [UCSC Family Browser]
SOURCE	NM_001065
SMD	Hs.713833
SAGE	Hs.713833
GO	receptor activity [Amigo]  receptor activity
GO	tumor necrosis factor receptor activity [Amigo]  tumor necrosis factor receptor activity
GO	protein binding [Amigo]  protein binding
GO	extracellular region [Amigo]  extracellular region
GO	plasma membrane [Amigo]  plasma membrane
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	prostaglandin metabolic process [Amigo]  prostaglandin metabolic process
GO	apoptosis [Amigo]  apoptosis
GO	signal transduction [Amigo]  signal transduction
GO	cytokine and chemokine mediated signaling pathway [Amigo]  cytokine and chemokine mediated signaling pathway
GO	positive regulation of I-kappaB kinase/NF-kappaB cascade [Amigo]  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO	interspecies interaction between organisms [Amigo]  interspecies interaction between organisms
GO	positive regulation of transcription from RNA polymerase II promoter [Amigo]  positive regulation of transcription from RNA polymerase II promoter
GO	positive regulation of inflammatory response [Amigo]  positive regulation of inflammatory response
BIOCARTA	HIV-I Nef: negative effector of Fas and TNF    [Genes]
BIOCARTA	Acetylation and Deacetylation of RelA in The Nucleus    [Genes]
BIOCARTA	Ceramide Signaling Pathway    [Genes]
BIOCARTA	Keratinocyte Differentiation    [Genes]
BIOCARTA	NF-kB Signaling Pathway    [Genes]
BIOCARTA	Regulation of transcriptional activity by PML    [Genes]
BIOCARTA	SODD/TNFR1 Signaling Pathway    [Genes]
BIOCARTA	TNF/Stress Related Signaling    [Genes]
BIOCARTA	Chaperones modulate interferon Signaling Pathway    [Genes]
BIOCARTA	TNFR1 Signaling Pathway    [Genes]
KEGG	MAPK signaling pathway
KEGG	Cytokine-cytokine receptor interaction
KEGG	Apoptosis
KEGG	Adipocytokine signaling pathway
PubGene	TNFRSF1A
TreeFam	TNFRSF1A
CTD	7132 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TNFRSF1A Related clones (RZPD - Berlin)
	PubMed
PubMed	223 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:35:39 2008