TRAF7 (TNF receptor-associated factor 7)

Identity

Other names	DKFZp586I021
	MGC7807
	RFWD1
	RNF119
HGNC	TRAF7
Location	16p13.3
Location_base_pair	Starts at 2145800 and ends at 2168131 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TRAF7   20456
Entrez_Gene	TRAF7  84231  TNF receptor-associated factor 7
	Cards
GeneCards	TRAF7
Ensembl	TRAF7 [Search_View]   ENSG00000131653 [Gene_View]
Genatlas	TRAF7
GeneLynx	TRAF7
eGenome	TRAF7
euGene	84231
	Genomic and cartography
GoldenPath	TRAF7  -  16p13.3   chr16:2145800-2168131 +  16p13.3   [Description]    (hg18-March_2006)
Ensembl	TRAF7 - 16p13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TRAF7
	Gene and transcription
Genbank	AK090624 [ ENTREZ ]
Genbank	AL136921 [ ENTREZ ]
Genbank	AW245178 [ ENTREZ ]
Genbank	AY569455 [ ENTREZ ]
Genbank	BC024267 [ ENTREZ ]
RefSeq	NM_032271 [ SRS ]    NM_032271 [ ENTREZ ]
RefSeq	AC_000059 [ SRS ]    AC_000059 [ ENTREZ ]
RefSeq	AC_000148 [ SRS ]    AC_000148 [ ENTREZ ]
RefSeq	NC_000016 [ SRS ]    NC_000016 [ ENTREZ ]
RefSeq	NT_037887 [ SRS ]    NT_037887 [ ENTREZ ]
RefSeq	NW_001838339 [ SRS ]    NW_001838339 [ ENTREZ ]
RefSeq	NW_926018 [ SRS ]    NW_926018 [ ENTREZ ]
AceView	TRAF7 AceView - NCBI
Unigene	Hs.713632 [ SRS ]    Hs.713632 [ NCBI ]     HS713632 [ spliceNest ]
Fast-db	2018 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q6Q0C0 [ SRS]    Q6Q0C0 [ EXPASY ]     Q6Q0C0 [ INTERPRO ]     Q6Q0C0 [ UNIPROT ]
Prosite	PS00678 WD_REPEATS_1 [ SRS ]    PS00678 WD_REPEATS_1 [ Expasy ]
Prosite	PS50082 WD_REPEATS_2 [ SRS ]    PS50082 WD_REPEATS_2 [ Expasy ]
Prosite	PS50294 WD_REPEATS_REGION [ SRS ]    PS50294 WD_REPEATS_REGION [ Expasy ]
Prosite	PS00518 ZF_RING_1 [ SRS ]    PS00518 ZF_RING_1 [ Expasy ]
Prosite	PS50089 ZF_RING_2 [ SRS ]    PS50089 ZF_RING_2 [ Expasy ]
Prosite	PS50145 ZF_TRAF [ SRS ]    PS50145 ZF_TRAF [ Expasy ]
Interpro	IPR015943 WD40/YVTN_repeat-like [ SRS ]    IPR015943 WD40/YVTN_repeat-like [ EBI ]
Interpro	IPR001680 WD40_repeat [ SRS ]    IPR001680 WD40_repeat [ EBI ]
Interpro	IPR001841 Znf_RING [ SRS ]    IPR001841 Znf_RING [ EBI ]
Interpro	IPR013083 Znf_RING/FYVE/PHD [ SRS ]    IPR013083 Znf_RING/FYVE/PHD [ EBI ]
Interpro	IPR001293 Znf_TRAF [ SRS ]    IPR001293 Znf_TRAF [ EBI ]
CluSTr	Q6Q0C0
Pfam	PF00400 WD40 [ SRS ]    PF00400 WD40 [ Sanger ]    pfam00400 [ NCBI-CDD ]
Pfam	PF00097 zf-C3HC4 [ SRS ]    PF00097 zf-C3HC4 [ Sanger ]    pfam00097 [ NCBI-CDD ]
Pfam	PF02176 zf-TRAF [ SRS ]    PF02176 zf-TRAF [ Sanger ]    pfam02176 [ NCBI-CDD ]
Smart	SM00184 RING [EMBL]
Smart	SM00320 WD40 [EMBL]
Prodom	PD000018 WD40[INRA-Toulouse]
Prodom	Q6Q0C0 TRAF7_HUMAN [ Domain structure ]   Q6Q0C0 TRAF7_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q6Q0C0
HPRD	06977
	Protein Interaction databases
DIP	Q6Q0C0
IntAct	Q6Q0C0
	Polymorphism : SNP, mutations, diseases
OMIM	606692    [ map ]
GENECLINICS	606692
SNP	TRAF7 [dbSNP-NCBI]
SNP	NM_032271 [SNP-NCI]
SNP	TRAF7 [GeneSNPs - Utah]  TRAF7] [HGBASE - SRS]
HAPMAP	TRAF7 [HAPMAP]
COSMIC	TRAF7 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TRAF7
	General knowledge
Family Browser	TRAF7 [UCSC Family Browser]
SOURCE	NM_032271
SMD	Hs.713632
SAGE	Hs.713632
Enzyme	6.3.2.- [ Enzyme-Expasy ]   6.3.2.- [ Enzyme-SRS ]   6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   6.3.2.- [ WIT ]
GO	ubiquitin ligase complex [Amigo]  ubiquitin ligase complex
GO	activation of MAPKKK activity [Amigo]  activation of MAPKKK activity
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	GTP binding [Amigo]  GTP binding
GO	transcription [Amigo]  transcription
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	zinc ion binding [Amigo]  zinc ion binding
GO	protein ubiquitination [Amigo]  protein ubiquitination
GO	ligase activity [Amigo]  ligase activity
GO	regulation of exocytosis [Amigo]  regulation of exocytosis
GO	intrinsic to plasma membrane [Amigo]  intrinsic to plasma membrane
GO	cytoplasmic vesicle [Amigo]  cytoplasmic vesicle
GO	exocrine system development [Amigo]  exocrine system development
GO	identical protein binding [Amigo]  identical protein binding
GO	regulation of apoptosis [Amigo]  regulation of apoptosis
GO	positive regulation of MAPKKK cascade [Amigo]  positive regulation of MAPKKK cascade
GO	metal ion binding [Amigo]  metal ion binding
KEGG	Tryptophan metabolism
PubGene	TRAF7
TreeFam	TRAF7
CTD	84231 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TRAF7 Related clones (RZPD - Berlin)
	PubMed
PubMed	6 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:36:09 2008