Identity
HGNC
LOCATION
12q13.12
LOCUSID
ALIAS
B-ALPHA-1,LIS3,TUBA3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7846
MIM: 602529
HGNC: 20766
Ensembl: ENSG00000167552
Variants:
dbSNP: 7846
ClinVar: 7846
TCGA: ENSG00000167552
COSMIC: TUBA1A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37873730 | 2023 | TUBA1A licenses APC/C-mediated mitotic progression to drive glioblastoma growth by inhibiting PLK3. | 0 |
| 37873730 | 2023 | TUBA1A licenses APC/C-mediated mitotic progression to drive glioblastoma growth by inhibiting PLK3. | 0 |
| 34508164 | 2022 | αTAT1-induced tubulin acetylation promotes ameloblastoma migration and invasion. | 5 |
| 35017693 | 2022 | Complementing the phenotypical spectrum of TUBA1A tubulinopathy and its role in early-onset epilepsies. | 6 |
| 35511030 | 2022 | TUBA1A tubulinopathy mutants disrupt neuron morphogenesis and override XMAP215/Stu2 regulation of microtubule dynamics. | 6 |
| 34508164 | 2022 | αTAT1-induced tubulin acetylation promotes ameloblastoma migration and invasion. | 5 |
| 35017693 | 2022 | Complementing the phenotypical spectrum of TUBA1A tubulinopathy and its role in early-onset epilepsies. | 6 |
| 35511030 | 2022 | TUBA1A tubulinopathy mutants disrupt neuron morphogenesis and override XMAP215/Stu2 regulation of microtubule dynamics. | 6 |
| 33649541 | 2021 | Novel variants in TUBA1A cause congenital fibrosis of the extraocular muscles with or without malformations of cortical brain development. | 11 |
| 34185819 | 2021 | Novel proteins associated with chronic intermittent hypoxia and obstructive sleep apnea: From rat model to clinical evidence. | 0 |
| 33649541 | 2021 | Novel variants in TUBA1A cause congenital fibrosis of the extraocular muscles with or without malformations of cortical brain development. | 11 |
| 34185819 | 2021 | Novel proteins associated with chronic intermittent hypoxia and obstructive sleep apnea: From rat model to clinical evidence. | 0 |
| 31574570 | 2020 | Tubulin mutations in brain development disorders: Why haploinsufficiency does not explain TUBA1A tubulinopathies. | 15 |
| 31767681 | 2020 | Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. | 22 |
| 31833200 | 2020 | Microcephaly with a simplified gyral pattern in a child with a de novo TUBA1A variant. | 4 |
Citation
Dessen P
TUBA1A (tubulin alpha 1a)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/42730/tuba1a
