TXK (TXK tyrosine kinase)

Identity

Other names	BTKL
	MGC22473
	PSCTK5
	PTK4
	RLK
	TKL
Hugo	TXK
Location	4p12
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	TXK
GDB	TXK
Entrez_Gene	TXK  7294  TXK tyrosine kinase
	Cards
GeneCards	TXK
Ensembl	TXK [Search_View]   ENSG00000074966 [Gene_View]
Genatlas	TXK
GeneLynx	TXK
eGenome	TXK
euGene	7294
	Genomic and cartography
GoldenPath	TXK  -  4p12   chr4:47763167-47831030 -  4p12   [Description]    (hg18-March_2006)
Ensembl	TXK - 4p12 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TXK
	Gene and transcription
Genbank	BC017829 [ ENTREZ ]
Genbank	DB103575 [ ENTREZ ]
Genbank	L27071 [ ENTREZ ]
RefSeq	NM_003328 [ SRS ]    NM_003328 [ ENTREZ ]
RefSeq	AC_000047 [ SRS ]    AC_000047 [ ENTREZ ]
RefSeq	NC_000004 [ SRS ]    NC_000004 [ ENTREZ ]
RefSeq	NT_006238 [ SRS ]    NT_006238 [ ENTREZ ]
RefSeq	NW_922073 [ SRS ]    NW_922073 [ ENTREZ ]
AceView	TXK AceView - NCBI
Unigene	Hs.479669 [ SRS ]    Hs.479669 [ NCBI ]     HS479669 [ spliceNest ]
Fast-db	4090 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P42681 [ SRS]    P42681 [ EXPASY ]     P42681 [ INTERPRO ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00109 PROTEIN_KINASE_TYR [ SRS ]    PS00109 PROTEIN_KINASE_TYR [ Expasy ]
Prosite	PS50001 SH2 [ SRS ]    PS50001 SH2 [ Expasy ]
Prosite	PS50002 SH3 [ SRS ]    PS50002 SH3 [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR000980 SH2 [ SRS ]    IPR000980 SH2 [ EBI ]
Interpro	IPR001452 SH3 [ SRS ]    IPR001452 SH3 [ EBI ]
Interpro	IPR001245 Tyr_pkinase [ SRS ]    IPR001245 Tyr_pkinase [ EBI ]
Interpro	IPR008266 Tyr_pkinase_AS [ SRS ]    IPR008266 Tyr_pkinase_AS [ EBI ]
CluSTr	P42681
Pfam	PF07714 Pkinase_Tyr [ SRS ]    PF07714 Pkinase_Tyr [ Sanger ]    pfam07714 [ NCBI-CDD ]
Pfam	PF00017 SH2 [ SRS ]    PF00017 SH2 [ Sanger ]    pfam00017 [ NCBI-CDD ]
Pfam	PF00018 SH3_1 [ SRS ]    PF00018 SH3_1 [ Sanger ]    pfam00018 [ NCBI-CDD ]
Smart	SM00252 SH2 [EMBL]
Smart	SM00326 SH3 [EMBL]
Smart	SM00219 TyrKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	P42681 TXK_HUMAN [ Domain structure ]   P42681 TXK_HUMAN  [ sequences sharing at least 1 domain ]
Prodom	PD000001[INRA-Toulouse]
Prodom	P42681 TXK_HUMAN [ Domain structure ]   P42681 TXK_HUMAN  [ sequences sharing at least 1 domain ]
Prodom	PD000001[INRA-Toulouse]
Prodom	P42681 TXK_HUMAN [ Domain structure ]   P42681 TXK_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P42681
PDB	2DM0 [ SRS ]    2DM0 [ PdbSum ],   2DM0 [ IMB ]   2DM0 [ RSDB ]
HPRD	02505
	Protein Interaction databases
DIP	P42681
IntAct	P42681
	Polymorphism : SNP, mutations, diseases
OMIM	600058    [ map ]
GENECLINICS	600058
SNP	TXK [dbSNP-NCBI]
SNP	NM_003328 [SNP-NCI]
SNP	TXK [GeneSNPs - Utah]  TXK] [HGBASE - SRS]
HAPMAP	TXK [HAPMAP]
COSMIC	TXK [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TXK
	General knowledge
Family Browser	TXK [UCSC Family Browser]
SOURCE	NM_003328
SMD	Hs.479669
SAGE	Hs.479669
Enzyme	2.7.10.2 [ Enzyme-SRS ]   2.7.10.2 [ Brenda-SRS ]   2.7.10.2 [ KEGG ]   2.7.10.2 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	non-membrane spanning protein tyrosine kinase activity [Amigo]  non-membrane spanning protein tyrosine kinase activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	transferase activity [Amigo]  transferase activity
KEGG	Leukocyte transendothelial migration
PubGene	TXK
TreeFam	TXK
CTD	7294 [Comparative Genomics Database]
	Other databases
	Probes
Probe	TXK Related clones (RZPD - Berlin)
	PubMed
PubMed	15 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:33:51 2008