TYRP1 (tyrosinase-related protein 1)

Identity

Other names	CAS2
	CATB
	GP75
	TRP
	TYRP
	b-PROTEIN
HGNC	TYRP1
Location	9p23
Location_base_pair	Starts at 12683386 and ends at 12700266 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TYRP1   12450
Entrez_Gene	TYRP1  7306  tyrosinase-related protein 1
	Cards
GeneCards	TYRP1
Ensembl	TYRP1 [Search_View]   ENSG00000107165 [Gene_View]
Genatlas	TYRP1
GeneLynx	TYRP1
eGenome	TYRP1
euGene	7306
	Genomic and cartography
GoldenPath	TYRP1  -  9p23   chr9:12683386-12700266 +  9p23   [Description]    (hg18-March_2006)
Ensembl	TYRP1 - 9p23 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TYRP1
	Gene and transcription
Genbank	AL600654 [ ENTREZ ]
Genbank	BC052608 [ ENTREZ ]
Genbank	CD679533 [ ENTREZ ]
Genbank	CR407683 [ ENTREZ ]
Genbank	DA278582 [ ENTREZ ]
RefSeq	NM_000550 [ SRS ]    NM_000550 [ ENTREZ ]
RefSeq	AC_000052 [ SRS ]    AC_000052 [ ENTREZ ]
RefSeq	AC_000141 [ SRS ]    AC_000141 [ ENTREZ ]
RefSeq	NC_000009 [ SRS ]    NC_000009 [ ENTREZ ]
RefSeq	NT_008413 [ SRS ]    NT_008413 [ ENTREZ ]
RefSeq	NW_001839149 [ SRS ]    NW_001839149 [ ENTREZ ]
RefSeq	NW_924062 [ SRS ]    NW_924062 [ ENTREZ ]
AceView	TYRP1 AceView - NCBI
Unigene	Hs.270279 [ SRS ]    Hs.270279 [ NCBI ]     HS270279 [ spliceNest ]
Fast-db	2307 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P17643 [ SRS]    P17643 [ EXPASY ]     P17643 [ INTERPRO ]     P17643 [ UNIPROT ]
Prosite	PS00497 TYROSINASE_1 [ SRS ]    PS00497 TYROSINASE_1 [ Expasy ]
Prosite	PS00498 TYROSINASE_2 [ SRS ]    PS00498 TYROSINASE_2 [ Expasy ]
Interpro	IPR015559 DHXI_oxidase [ SRS ]    IPR015559 DHXI_oxidase [ EBI ]
Interpro	IPR008922 Di-copper_centre [ SRS ]    IPR008922 Di-copper_centre [ EBI ]
Interpro	IPR002227 Tyrosinase [ SRS ]    IPR002227 Tyrosinase [ EBI ]
CluSTr	P17643
Pfam	PF00264 Tyrosinase [ SRS ]    PF00264 Tyrosinase [ Sanger ]    pfam00264 [ NCBI-CDD ]
Blocks	P17643
HPRD	00283
	Protein Interaction databases
DIP	P17643
IntAct	P17643
	Polymorphism : SNP, mutations, diseases
OMIM	115501;203290;278400    [ map ]
GENECLINICS	115501;203290;278400
SNP	TYRP1 [dbSNP-NCBI]
SNP	NM_000550 [SNP-NCI]
SNP	TYRP1 [GeneSNPs - Utah]  TYRP1] [HGBASE - SRS]
HAPMAP	TYRP1 [HAPMAP]
COSMIC	TYRP1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TYRP1
	General knowledge
Family Browser	TYRP1 [UCSC Family Browser]
SOURCE	NM_000550
SMD	Hs.270279
SAGE	Hs.270279
Enzyme	1.14.18.- [ Enzyme-Expasy ]   1.14.18.- [ Enzyme-SRS ]   1.14.18.- [ IntEnz-EBI ]   1.14.18.- [ BRENDA ]   1.14.18.- [ KEGG ]   1.14.18.- [ WIT ]
GO	monooxygenase activity [Amigo]  monooxygenase activity
GO	copper ion binding [Amigo]  copper ion binding
GO	protein binding [Amigo]  protein binding
GO	melanin biosynthetic process from tyrosine [Amigo]  melanin biosynthetic process from tyrosine
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	melanosome membrane [Amigo]  melanosome membrane
GO	protein homodimerization activity [Amigo]  protein homodimerization activity
GO	metal ion binding [Amigo]  metal ion binding
GO	protein heterodimerization activity [Amigo]  protein heterodimerization activity
GO	oxidation reduction [Amigo]  oxidation reduction
KEGG	Tyrosine metabolism
PubGene	TYRP1
TreeFam	TYRP1
CTD	7306 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TYRP1 Related clones (RZPD - Berlin)
	PubMed
PubMed	42 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 15:06:31 2008