UBE2B (ubiquitin-conjugating enzyme E2B (RAD6 homolog))

Identity

Other names	E2-17kDa
	HHR6B
	HR6B
	RAD6B
	UBC2
HGNC	UBE2B
Location	5q31.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	UBE2B   12473
Entrez_Gene	UBE2B  7320  ubiquitin-conjugating enzyme E2B (RAD6 homolog)
	Cards
GeneCards	UBE2B
Ensembl	UBE2B [Search_View]   ENSG00000119048 [Gene_View]
Genatlas	UBE2B
GeneLynx	UBE2B
eGenome	UBE2B
euGene	7320
	Genomic and cartography
GoldenPath	UBE2B  -  5q31.1   chr5:133734769-133755698 +  5q31.1   [Description]    (hg18-March_2006)
Ensembl	UBE2B - 5q31.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	UBE2B
	Gene and transcription
Genbank	AK312012 [ ENTREZ ]
Genbank	BC001694 [ ENTREZ ]
Genbank	BC005979 [ ENTREZ ]
Genbank	BC008404 [ ENTREZ ]
Genbank	BC008470 [ ENTREZ ]
RefSeq	NM_003337 [ SRS ]    NM_003337 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_034772 [ SRS ]    NT_034772 [ ENTREZ ]
RefSeq	NW_001838952 [ SRS ]    NW_001838952 [ ENTREZ ]
RefSeq	NW_922784 [ SRS ]    NW_922784 [ ENTREZ ]
AceView	UBE2B AceView - NCBI
Unigene	Hs.644421 [ SRS ]    Hs.644421 [ NCBI ]     HS644421 [ spliceNest ]
Fast-db	9805 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P63146 [ SRS]    P63146 [ EXPASY ]     P63146 [ INTERPRO ]     P63146 [ UNIPROT ]
Prosite	PS00183 UBIQUITIN_CONJUGAT_1 [ SRS ]    PS00183 UBIQUITIN_CONJUGAT_1 [ Expasy ]
Prosite	PS50127 UBIQUITIN_CONJUGAT_2 [ SRS ]    PS50127 UBIQUITIN_CONJUGAT_2 [ Expasy ]
Interpro	IPR016135 UBQ-conjugat/RWD-like [ SRS ]    IPR016135 UBQ-conjugat/RWD-like [ EBI ]
Interpro	IPR000608 UBQ-conjugat_E2 [ SRS ]    IPR000608 UBQ-conjugat_E2 [ EBI ]
CluSTr	P63146
Pfam	PF00179 UQ_con [ SRS ]    PF00179 UQ_con [ Sanger ]    pfam00179 [ NCBI-CDD ]
Smart	SM00212 UBCc [EMBL]
Prodom	PD000461 UBQ_conjugat[INRA-Toulouse]
Prodom	P63146 UBE2B_HUMAN [ Domain structure ]   P63146 UBE2B_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P63146
PDB	1JAS [ SRS ]    1JAS [ PdbSum ],   1JAS [ IMB ]   1JAS [ RSDB ]
PDB	1NXA [ SRS ]    1NXA [ PdbSum ],   1NXA [ IMB ]   1NXA [ RSDB ]
HPRD	01533
	Protein Interaction databases
DIP	P63146
IntAct	P63146
	Polymorphism : SNP, mutations, diseases
OMIM	179095    [ map ]
GENECLINICS	179095
SNP	UBE2B [dbSNP-NCBI]
SNP	NM_003337 [SNP-NCI]
SNP	UBE2B [GeneSNPs - Utah]  UBE2B] [HGBASE - SRS]
HAPMAP	UBE2B [HAPMAP]
COSMIC	UBE2B [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	UBE2B
	General knowledge
Family Browser	UBE2B [UCSC Family Browser]
SOURCE	NM_003337
SMD	Hs.644421
SAGE	Hs.644421
Enzyme	6.3.2.19 [ Enzyme-Expasy ]   6.3.2.19 [ Enzyme-SRS ]   6.3.2.19 [ IntEnz-EBI ]   6.3.2.19 [ BRENDA ]   6.3.2.19 [ KEGG ]   6.3.2.19 [ WIT ]
GO	chromatin [Amigo]  chromatin
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	plasma membrane [Amigo]  plasma membrane
GO	postreplication repair [Amigo]  postreplication repair
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	sperm axoneme assembly [Amigo]  sperm axoneme assembly
GO	ligase activity [Amigo]  ligase activity
GO	regulation of protein metabolic process [Amigo]  regulation of protein metabolic process
PubGene	UBE2B
TreeFam	UBE2B
CTD	7320 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	UBE2B Related clones (RZPD - Berlin)
	PubMed
PubMed	20 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Sep 29 18:27:50 2008