UBE2E1 (ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast))

Identity

Other names	UBCH6
HGNC	UBE2E1
Location	3p24.2
Location_base_pair	Starts at 23822443 and ends at 23907811 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	UBE2E1   12477
Entrez_Gene	UBE2E1  7324  ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
	Cards
GeneCards	UBE2E1
Ensembl	UBE2E1 [Search_View]   ENSG00000170142 [Gene_View]
Genatlas	UBE2E1
GeneLynx	UBE2E1
eGenome	UBE2E1
euGene	7324
	Genomic and cartography
GoldenPath	UBE2E1  -  3p24.2   chr3:23822443-23907811 +  3p24.2   [Description]    (hg18-March_2006)
Ensembl	UBE2E1 - 3p24.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	UBE2E1
	Gene and transcription
Genbank	AK314854 [ ENTREZ ]
Genbank	BC009139 [ ENTREZ ]
Genbank	BF698653 [ ENTREZ ]
Genbank	BI223271 [ ENTREZ ]
Genbank	CR605474 [ ENTREZ ]
RefSeq	NM_003341 [ SRS ]    NM_003341 [ ENTREZ ]
RefSeq	NM_182666 [ SRS ]    NM_182666 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838877 [ SRS ]    NW_001838877 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
AceView	UBE2E1 AceView - NCBI
Unigene	Hs.164853 [ SRS ]    Hs.164853 [ NCBI ]     HS164853 [ spliceNest ]
Fast-db	3021 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P51965 [ SRS]    P51965 [ EXPASY ]     P51965 [ INTERPRO ]     P51965 [ UNIPROT ]
Prosite	PS00183 UBIQUITIN_CONJUGAT_1 [ SRS ]    PS00183 UBIQUITIN_CONJUGAT_1 [ Expasy ]
Prosite	PS50127 UBIQUITIN_CONJUGAT_2 [ SRS ]    PS50127 UBIQUITIN_CONJUGAT_2 [ Expasy ]
Interpro	IPR016135 UBQ-conjugat/RWD-like [ SRS ]    IPR016135 UBQ-conjugat/RWD-like [ EBI ]
Interpro	IPR000608 UBQ-conjugat_E2 [ SRS ]    IPR000608 UBQ-conjugat_E2 [ EBI ]
CluSTr	P51965
Pfam	PF00179 UQ_con [ SRS ]    PF00179 UQ_con [ Sanger ]    pfam00179 [ NCBI-CDD ]
Smart	SM00212 UBCc [EMBL]
Prodom	PD000461 UBQ_conjugat[INRA-Toulouse]
Prodom	P51965 UB2E1_HUMAN [ Domain structure ]   P51965 UB2E1_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P51965
PDB	1XR9 [ SRS ]    1XR9 [ PdbSum ],   1XR9 [ IMB ]   1XR9 [ RSDB ]
PDB	3BZH [ SRS ]    3BZH [ PdbSum ],   3BZH [ IMB ]   3BZH [ RSDB ]
HPRD	04225
	Protein Interaction databases
DIP	P51965
IntAct	P51965
	Polymorphism : SNP, mutations, diseases
OMIM	602916    [ map ]
GENECLINICS	602916
SNP	UBE2E1 [dbSNP-NCBI]
SNP	NM_003341 [SNP-NCI]
SNP	NM_182666 [SNP-NCI]
SNP	UBE2E1 [GeneSNPs - Utah]  UBE2E1] [HGBASE - SRS]
HAPMAP	UBE2E1 [HAPMAP]
COSMIC	UBE2E1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	UBE2E1
	General knowledge
Family Browser	UBE2E1 [UCSC Family Browser]
SOURCE	NM_003341
SOURCE	NM_182666
SMD	Hs.164853
SAGE	Hs.164853
Enzyme	6.3.2.19 [ Enzyme-Expasy ]   6.3.2.19 [ Enzyme-SRS ]   6.3.2.19 [ IntEnz-EBI ]   6.3.2.19 [ BRENDA ]   6.3.2.19 [ KEGG ]   6.3.2.19 [ WIT ]
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	protein binding [Amigo]  protein binding
GO	nucleoplasm [Amigo]  nucleoplasm
GO	cytosol [Amigo]  cytosol
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	ligase activity [Amigo]  ligase activity
GO	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [Amigo]  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO	ISG15-protein conjugation [Amigo]  ISG15-protein conjugation
GO	ISG15 ligase activity [Amigo]  ISG15 ligase activity
GO	regulation of protein metabolic process [Amigo]  regulation of protein metabolic process
GO	negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Amigo]  negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO	positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Amigo]  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
KEGG	Ubiquitin mediated proteolysis
PubGene	UBE2E1
TreeFam	UBE2E1
CTD	7324 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	UBE2E1 Related clones (RZPD - Berlin)
	PubMed
PubMed	25 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 15:06:37 2008