UBE2M (ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast))

Identity

Other names	UBC-RS2
	UBC12
	hUbc12
HGNC	UBE2M
Location	19q13.43
Location_base_pair	Starts at 63758891 and ends at 63762155 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	UBE2M   12491
Entrez_Gene	UBE2M  9040  ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
	Cards
GeneCards	UBE2M
Ensembl	UBE2M [Search_View]   ENSG00000130725 [Gene_View]
Genatlas	UBE2M
GeneLynx	UBE2M
eGenome	UBE2M
euGene	9040
	Genomic and cartography
GoldenPath	UBE2M  -  19q13.43   chr19:63758891-63762155 -  19q13.43   [Description]    (hg18-March_2006)
Ensembl	UBE2M - 19q13.43 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	UBE2M
	Gene and transcription
Genbank	AB012191 [ ENTREZ ]
Genbank	AF075599 [ ENTREZ ]
Genbank	AL569047 [ ENTREZ ]
Genbank	BC058924 [ ENTREZ ]
Genbank	BM559596 [ ENTREZ ]
RefSeq	NM_003969 [ SRS ]    NM_003969 [ ENTREZ ]
RefSeq	AC_000062 [ SRS ]    AC_000062 [ ENTREZ ]
RefSeq	AC_000151 [ SRS ]    AC_000151 [ ENTREZ ]
RefSeq	NC_000019 [ SRS ]    NC_000019 [ ENTREZ ]
RefSeq	NT_011109 [ SRS ]    NT_011109 [ ENTREZ ]
RefSeq	NW_001838501 [ SRS ]    NW_001838501 [ ENTREZ ]
RefSeq	NW_927284 [ SRS ]    NW_927284 [ ENTREZ ]
AceView	UBE2M AceView - NCBI
Unigene	Hs.406068 [ SRS ]    Hs.406068 [ NCBI ]     HS406068 [ spliceNest ]
Fast-db	15785 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P61081 [ SRS]    P61081 [ EXPASY ]     P61081 [ INTERPRO ]     P61081 [ UNIPROT ]
Prosite	PS00183 UBIQUITIN_CONJUGAT_1 [ SRS ]    PS00183 UBIQUITIN_CONJUGAT_1 [ Expasy ]
Prosite	PS50127 UBIQUITIN_CONJUGAT_2 [ SRS ]    PS50127 UBIQUITIN_CONJUGAT_2 [ Expasy ]
Interpro	IPR015580 Ubc12 [ SRS ]    IPR015580 Ubc12 [ EBI ]
Interpro	IPR016135 UBQ-conjugat/RWD-like [ SRS ]    IPR016135 UBQ-conjugat/RWD-like [ EBI ]
Interpro	IPR000608 UBQ-conjugat_E2 [ SRS ]    IPR000608 UBQ-conjugat_E2 [ EBI ]
CluSTr	P61081
Pfam	PF00179 UQ_con [ SRS ]    PF00179 UQ_con [ Sanger ]    pfam00179 [ NCBI-CDD ]
Smart	SM00212 UBCc [EMBL]
Prodom	PD000461 UBQ_conjugat[INRA-Toulouse]
Prodom	P61081 UBC12_HUMAN [ Domain structure ]   P61081 UBC12_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P61081
PDB	1TT5 [ SRS ]    1TT5 [ PdbSum ],   1TT5 [ IMB ]   1TT5 [ RSDB ]
PDB	1Y8X [ SRS ]    1Y8X [ PdbSum ],   1Y8X [ IMB ]   1Y8X [ RSDB ]
PDB	2NVU [ SRS ]    2NVU [ PdbSum ],   2NVU [ IMB ]   2NVU [ RSDB ]
HPRD	04414
	Protein Interaction databases
DIP	P61081
IntAct	P61081
	Polymorphism : SNP, mutations, diseases
OMIM	603173    [ map ]
GENECLINICS	603173
SNP	UBE2M [dbSNP-NCBI]
SNP	NM_003969 [SNP-NCI]
SNP	UBE2M [GeneSNPs - Utah]  UBE2M] [HGBASE - SRS]
HAPMAP	UBE2M [HAPMAP]
COSMIC	UBE2M [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	UBE2M
	General knowledge
Family Browser	UBE2M [UCSC Family Browser]
SOURCE	NM_003969
SMD	Hs.406068
SAGE	Hs.406068
Enzyme	6.3.2.- [ Enzyme-Expasy ]   6.3.2.- [ Enzyme-SRS ]   6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   6.3.2.- [ WIT ]
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	protein binding [Amigo]  protein binding
GO	cellular_component [Amigo]  cellular_component
GO	ligase activity [Amigo]  ligase activity
GO	ribosomal S6-glutamic acid ligase activity [Amigo]  ribosomal S6-glutamic acid ligase activity
GO	regulation of protein metabolic process [Amigo]  regulation of protein metabolic process
BIOCARTA	Regulation of p27 Phosphorylation during Cell Cycle Progression    [Genes]
PubGene	UBE2M
TreeFam	UBE2M
CTD	9040 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	UBE2M Related clones (RZPD - Berlin)
	PubMed
PubMed	11 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:37:05 2008