UCHL1 (ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase))

Identity

Other names	PARK5
	PGP9.5
	Uch-L1
Hugo	UCHL1
Location	4p14
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	UCHL1
GDB	UCHL1
Entrez_Gene	UCHL1  7345  ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
	Cards
GeneCards	UCHL1
Ensembl	UCHL1 [Search_View]   ENSG00000154277 [Gene_View]
Genatlas	UCHL1
GeneLynx	UCHL1
eGenome	UCHL1
euGene	7345
	Genomic and cartography
GoldenPath	UCHL1  -  4p14   chr4:40953686-40965202 +  4p13   [Description]    (hg18-March_2006)
Ensembl	UCHL1 - 4p13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	UCHL1
	Gene and transcription
Genbank	AK054579 [ ENTREZ ]
Genbank	BC000332 [ ENTREZ ]
Genbank	BC005117 [ ENTREZ ]
Genbank	BC006305 [ ENTREZ ]
Genbank	BC018838 [ ENTREZ ]
RefSeq	NM_004181 [ SRS ]    NM_004181 [ ENTREZ ]
RefSeq	AC_000047 [ SRS ]    AC_000047 [ ENTREZ ]
RefSeq	NC_000004 [ SRS ]    NC_000004 [ ENTREZ ]
RefSeq	NT_006238 [ SRS ]    NT_006238 [ ENTREZ ]
RefSeq	NW_922073 [ SRS ]    NW_922073 [ ENTREZ ]
AceView	UCHL1 AceView - NCBI
Unigene	Hs.518731 [ SRS ]    Hs.518731 [ NCBI ]     HS518731 [ spliceNest ]
Fast-db	3812 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P09936 [ SRS]    P09936 [ EXPASY ]     P09936 [ INTERPRO ]
Prosite	PS00140 UCH_1 [ SRS ]    PS00140 UCH_1 [ Expasy ]
Interpro	IPR001578 Peptidase_C12 [ SRS ]    IPR001578 Peptidase_C12 [ EBI ]
CluSTr	P09936
Pfam	PF01088 Peptidase_C12 [ SRS ]    PF01088 Peptidase_C12 [ Sanger ]    pfam01088 [ NCBI-CDD ]
Prodom	PD350662 Peptidase_C12[INRA-Toulouse]
Prodom	P09936 UCHL1_HUMAN [ Domain structure ]   P09936 UCHL1_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P09936
PDB	2ETL [ SRS ]    2ETL [ PdbSum ],   2ETL [ IMB ]   2ETL [ RSDB ]
HPRD	01877
	Protein Interaction databases
DIP	P09936
IntAct	P09936
	Polymorphism : SNP, mutations, diseases
OMIM	168600;191342    [ map ]
GENECLINICS	168600;191342
SNP	UCHL1 [dbSNP-NCBI]
SNP	NM_004181 [SNP-NCI]
SNP	UCHL1 [GeneSNPs - Utah]  UCHL1] [HGBASE - SRS]
HAPMAP	UCHL1 [HAPMAP]
HGMD	UCHL1
	General knowledge
Family Browser	UCHL1 [UCSC Family Browser]
SOURCE	NM_004181
SMD	Hs.518731
SAGE	Hs.518731
Enzyme	3.4.19.12 [ Enzyme-SRS ]   3.4.19.12 [ Brenda-SRS ]   3.4.19.12 [ KEGG ]   3.4.19.12 [ WIT ]
GO	cysteine-type endopeptidase activity [Amigo]  cysteine-type endopeptidase activity
GO	ubiquitin thiolesterase activity [Amigo]  ubiquitin thiolesterase activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	cytoplasm [Amigo]  cytoplasm
GO	cytoplasm [Amigo]  cytoplasm
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	omega peptidase activity [Amigo]  omega peptidase activity
GO	protein deubiquitination [Amigo]  protein deubiquitination
GO	ligase activity [Amigo]  ligase activity
GO	ubiquitin binding [Amigo]  ubiquitin binding
KEGG	Neurodegenerative Disorders
KEGG	Parkinson's disease
PubGene	UCHL1
TreeFam	UCHL1
CTD	7345 [Comparative Genomics Database]
	Other databases
	Probes
Probe	UCHL1 Related clones (RZPD - Berlin)
	PubMed
PubMed	56 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:34:19 2008