USP8 (ubiquitin specific peptidase 8)

Identity

Other names	FLJ34456
	HumORF8
	KIAA0055
	MGC129718
	UBPY
HGNC	USP8
Location	15q21.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	USP8   12631
Entrez_Gene	USP8  9101  ubiquitin specific peptidase 8
	Cards
GeneCards	USP8
Ensembl	USP8 [Search_View]   ENSG00000138592 [Gene_View]
Genatlas	USP8
GeneLynx	USP8
eGenome	USP8
euGene	9101
	Genomic and cartography
GoldenPath	USP8  -  15q21.1   chr15:48503871-48580569 +  15q21.2   [Description]    (hg18-March_2006)
Ensembl	USP8 - 15q21.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	USP8
	Gene and transcription
Genbank	AA399951 [ ENTREZ ]
Genbank	AA773713 [ ENTREZ ]
Genbank	AK091775 [ ENTREZ ]
Genbank	AK292400 [ ENTREZ ]
Genbank	BC015545 [ ENTREZ ]
RefSeq	NM_001128610 [ SRS ]    NM_001128610 [ ENTREZ ]
RefSeq	NM_001128611 [ SRS ]    NM_001128611 [ ENTREZ ]
RefSeq	NM_005154 [ SRS ]    NM_005154 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	AC_000147 [ SRS ]    AC_000147 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_001838218 [ SRS ]    NW_001838218 [ ENTREZ ]
RefSeq	NW_925884 [ SRS ]    NW_925884 [ ENTREZ ]
AceView	USP8 AceView - NCBI
Unigene	Hs.644563 [ SRS ]    Hs.644563 [ NCBI ]     HS644563 [ spliceNest ]
Fast-db	5134 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P40818 [ SRS]    P40818 [ EXPASY ]     P40818 [ INTERPRO ]     P40818 [ UNIPROT ]
Prosite	PS50206 RHODANESE_3 [ SRS ]    PS50206 RHODANESE_3 [ Expasy ]
Prosite	PS00972 UCH_2_1 [ SRS ]    PS00972 UCH_2_1 [ Expasy ]
Prosite	PS00973 UCH_2_2 [ SRS ]    PS00973 UCH_2_2 [ Expasy ]
Prosite	PS50235 UCH_2_3 [ SRS ]    PS50235 UCH_2_3 [ Expasy ]
Interpro	IPR015063 DUF1873 [ SRS ]    IPR015063 DUF1873 [ EBI ]
Interpro	IPR001394 Peptidase_C19 [ SRS ]    IPR001394 Peptidase_C19 [ EBI ]
Interpro	IPR001763 Rhodanese-like [ SRS ]    IPR001763 Rhodanese-like [ EBI ]
CluSTr	P40818
Pfam	PF08969 DUF1873 [ SRS ]    PF08969 DUF1873 [ Sanger ]    pfam08969 [ NCBI-CDD ]
Pfam	PF00581 Rhodanese [ SRS ]    PF00581 Rhodanese [ Sanger ]    pfam00581 [ NCBI-CDD ]
Pfam	PF00443 UCH [ SRS ]    PF00443 UCH [ Sanger ]    pfam00443 [ NCBI-CDD ]
Smart	SM00450 RHOD [EMBL]
Blocks	P40818
PDB	1WHB [ SRS ]    1WHB [ PdbSum ],   1WHB [ IMB ]   1WHB [ RSDB ]
PDB	2A9U [ SRS ]    2A9U [ PdbSum ],   2A9U [ IMB ]   2A9U [ RSDB ]
PDB	2GFO [ SRS ]    2GFO [ PdbSum ],   2GFO [ IMB ]   2GFO [ RSDB ]
PDB	2GWF [ SRS ]    2GWF [ PdbSum ],   2GWF [ IMB ]   2GWF [ RSDB ]
HPRD	04405
	Protein Interaction databases
DIP	P40818
IntAct	P40818
	Polymorphism : SNP, mutations, diseases
OMIM	603158    [ map ]
GENECLINICS	603158
SNP	USP8 [dbSNP-NCBI]
SNP	NM_001128610 [SNP-NCI]
SNP	NM_001128611 [SNP-NCI]
SNP	NM_005154 [SNP-NCI]
SNP	USP8 [GeneSNPs - Utah]  USP8] [HGBASE - SRS]
HAPMAP	USP8 [HAPMAP]
COSMIC	USP8 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	USP8
	General knowledge
Family Browser	USP8 [UCSC Family Browser]
SOURCE	NM_001128610
SOURCE	NM_001128611
SOURCE	NM_005154
SMD	Hs.644563
SAGE	Hs.644563
Enzyme	3.1.2.15 [ Enzyme-Expasy ]   3.1.2.15 [ Enzyme-SRS ]   3.1.2.15 [ IntEnz-EBI ]   3.1.2.15 [ BRENDA ]   3.1.2.15 [ KEGG ]   3.1.2.15 [ WIT ]
GO	cysteine-type endopeptidase activity [Amigo]  cysteine-type endopeptidase activity
GO	ubiquitin thiolesterase activity [Amigo]  ubiquitin thiolesterase activity
GO	protein binding [Amigo]  protein binding
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	cell proliferation [Amigo]  cell proliferation
PubGene	USP8
TreeFam	USP8
CTD	9101 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	USP8 Related clones (RZPD - Berlin)
	PubMed
PubMed	23 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:37:44 2008