WAS (Wiskott-Aldrich syndrome (eczema-thrombocytopenia))

Identity

Other names	IMD2
	THC
	WASP
HGNC	WAS
Location	Xp11.4-p11.21
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	WAS   12731
Entrez_Gene	WAS  7454  Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
	Cards
GeneCards	WAS
Ensembl	WAS [Search_View]   ENSG00000015285 [Gene_View]
Genatlas	WAS
GeneLynx	WAS
eGenome	WAS
euGene	7454
	Genomic and cartography
GoldenPath	WAS  -     chrX:48427130-48434761 +  Xp11.23   [Description]    (hg18-March_2006)
Ensembl	WAS - Xp11.23 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	WAS
	Gene and transcription
Genbank	BC002961 [ ENTREZ ]
Genbank	BC012738 [ ENTREZ ]
Genbank	BI910072 [ ENTREZ ]
Genbank	CF529565 [ ENTREZ ]
Genbank	CR591854 [ ENTREZ ]
RefSeq	NM_000377 [ SRS ]    NM_000377 [ ENTREZ ]
RefSeq	AC_000066 [ SRS ]    AC_000066 [ ENTREZ ]
RefSeq	AC_000155 [ SRS ]    AC_000155 [ ENTREZ ]
RefSeq	NC_000023 [ SRS ]    NC_000023 [ ENTREZ ]
RefSeq	NG_007877 [ SRS ]    NG_007877 [ ENTREZ ]
RefSeq	NT_079573 [ SRS ]    NT_079573 [ ENTREZ ]
RefSeq	NW_001842363 [ SRS ]    NW_001842363 [ ENTREZ ]
RefSeq	NW_927703 [ SRS ]    NW_927703 [ ENTREZ ]
AceView	WAS AceView - NCBI
Unigene	Hs.2157 [ SRS ]    Hs.2157 [ NCBI ]     HS2157 [ spliceNest ]
Fast-db	7763 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P42768 [ SRS]    P42768 [ EXPASY ]     P42768 [ INTERPRO ]     P42768 [ UNIPROT ]
Prosite	PS50108 CRIB [ SRS ]    PS50108 CRIB [ Expasy ]
Prosite	PS50229 WH1 [ SRS ]    PS50229 WH1 [ Expasy ]
Prosite	PS51082 WH2 [ SRS ]    PS51082 WH2 [ Expasy ]
Interpro	IPR000697 EVH1 [ SRS ]    IPR000697 EVH1 [ EBI ]
Interpro	IPR000095 PAK_box_Rho_bd [ SRS ]    IPR000095 PAK_box_Rho_bd [ EBI ]
Interpro	IPR011993 PH_type [ SRS ]    IPR011993 PH_type [ EBI ]
Interpro	IPR003124 WH2_actin_bd [ SRS ]    IPR003124 WH2_actin_bd [ EBI ]
CluSTr	P42768
Pfam	PF00786 PBD [ SRS ]    PF00786 PBD [ Sanger ]    pfam00786 [ NCBI-CDD ]
Pfam	PF00568 WH1 [ SRS ]    PF00568 WH1 [ Sanger ]    pfam00568 [ NCBI-CDD ]
Pfam	PF02205 WH2 [ SRS ]    PF02205 WH2 [ Sanger ]    pfam02205 [ NCBI-CDD ]
Smart	SM00285 PBD [EMBL]
Smart	SM00461 WH1 [EMBL]
Smart	SM00246 WH2 [EMBL]
Blocks	P42768
PDB	1CEE [ SRS ]    1CEE [ PdbSum ],   1CEE [ IMB ]   1CEE [ RSDB ]
PDB	1EJ5 [ SRS ]    1EJ5 [ PdbSum ],   1EJ5 [ IMB ]   1EJ5 [ RSDB ]
PDB	1T84 [ SRS ]    1T84 [ PdbSum ],   1T84 [ IMB ]   1T84 [ RSDB ]
PDB	2A3Z [ SRS ]    2A3Z [ PdbSum ],   2A3Z [ IMB ]   2A3Z [ RSDB ]
HPRD	02314
	Protein Interaction databases
DIP	P42768
IntAct	P42768
	Polymorphism : SNP, mutations, diseases
OMIM	300299;300392;301000;313900    [ map ]
GENECLINICS	300299;300392;301000;313900
SNP	WAS [dbSNP-NCBI]
SNP	NM_000377 [SNP-NCI]
SNP	WAS [GeneSNPs - Utah]  WAS] [HGBASE - SRS]
HAPMAP	WAS [HAPMAP]
COSMIC	WAS [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	WAS
	General knowledge
Family Browser	WAS [UCSC Family Browser]
SOURCE	NM_000377
SMD	Hs.2157
SAGE	Hs.2157
GO	small GTPase regulator activity [Amigo]  small GTPase regulator activity
GO	cytoplasm [Amigo]  cytoplasm
GO	protein complex assembly [Amigo]  protein complex assembly
GO	defense response [Amigo]  defense response
GO	immune response [Amigo]  immune response
GO	blood coagulation [Amigo]  blood coagulation
GO	epidermis development [Amigo]  epidermis development
GO	vesicle membrane [Amigo]  vesicle membrane
GO	actin cytoskeleton [Amigo]  actin cytoskeleton
GO	endosome transport [Amigo]  endosome transport
GO	actin filament polymerization [Amigo]  actin filament polymerization
GO	actin filament-based movement [Amigo]  actin filament-based movement
GO	T cell activation [Amigo]  T cell activation
GO	identical protein binding [Amigo]  identical protein binding
KEGG	Adherens junction
KEGG	Regulation of actin cytoskeleton
PubGene	WAS
TreeFam	WAS
CTD	7454 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	WAS Related clones (RZPD - Berlin)
	PubMed
PubMed	122 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:38:06 2008