WNT2B (Wnt family member 2B)

2003-02-01  

Identity

HGNC
LOCATION
1p13.2
LOCUSID
ALIAS
WNT13

Other Information

Locus ID:

NCBI: 7482
MIM: 601968
HGNC: 12781
Ensembl: ENSG00000134245

Variants:

dbSNP: 7482
ClinVar: 7482
TCGA: ENSG00000134245
COSMIC: WNT2B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134245ENST00000256640Q5TEH8
ENSG00000134245ENST00000369684Q93097
ENSG00000134245ENST00000369686Q93097

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
Wnt signaling pathwayKEGGko04310
MelanogenesisKEGGko04916
Basal cell carcinomaKEGGko05217
mTOR signaling pathwayKEGGhsa04150
Wnt signaling pathwayKEGGhsa04310
MelanogenesisKEGGhsa04916
Pathways in cancerKEGGhsa05200
Basal cell carcinomaKEGGhsa05217
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Proteoglycans in cancerKEGGhsa05205
Proteoglycans in cancerKEGGko05205
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Wnt signalingKEGGhsa_M00677
Wnt signalingKEGGM00677
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Signaling by WntREACTOMER-HSA-195721
WNT ligand biogenesis and traffickingREACTOMER-HSA-3238698
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
120724092002Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs.39
237852852013Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses.29
186069512008Association study of Wnt signaling pathway genes in bipolar disorder.28
252979252014miR-185-3p regulates nasopharyngeal carcinoma radioresistance by targeting WNT2B in vitro.23
208197782010MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.21
193603542009Transcriptional regulation of WNT2B based on the balance of Hedgehog, Notch, BMP and WNT signals.18
196508452010CLC- a novel susceptibility gene for allergic rhinitis?14
251208492014Expression of Gli1 and Wnt2B correlates with progression and clinical outcome of pancreatic cancer.13
162732932005WNT2B: comparative integromics and clinical applications (Review).12

Citation

Dessen P

WNT2B (Wnt family member 2B)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42821/wnt2b