| Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells. |
| Ried K, Finnis M, Hobson L, Mangelsdorf M, Dayan S, Nancarrow JK, Woollatt E, Kremmidiotis G, Gardner A, Venter D, Baker E, Richards RI |
| Human molecular genetics. 2000 ; 9 (11) : 1651-1663. |
| PMID 10861292 |
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| WWOX, the FRA16D gene, behaves as a suppressor of tumor growth. |
| Bednarek AK, Keck-Waggoner CL, Daniel RL, Laflin KJ, Bergsagel PL, Kiguchi K, Brenner AJ, Aldaz CM |
| Cancer research. 2001 ; 61 (22) : 8068-8073. |
| PMID 11719429 |
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| WWOX: a candidate tumor suppressor gene involved in multiple tumor types. |
| Paige AJ, Taylor KJ, Taylor C, Hillier SG, Farrington S, Scott D, Porteous DJ, Smyth JF, Gabra H, Watson JE |
| Proceedings of the National Academy of Sciences of the United States of America. 2001 ; 98 (20) : 11417-11422. |
| PMID 11572989 |
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| Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma. |
| Kuroki T, Trapasso F, Shiraishi T, Alder H, Mimori K, Mori M, Croce CM |
| Cancer research. 2002 ; 62 (8) : 2258-2260. |
| PMID 11956080 |
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| WWOX, the common chromosomal fragile site, FRA16D, cancer gene. |
| Ludes-Meyers JH, Bednarek AK, Popescu NC, Bedford M, Aldaz CM |
| Cytogenetic and genome research. 2003 ; 100 (1-4) : 101-110. |
| PMID 14526170 |
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| WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer. |
| Yendamuri S, Kuroki T, Trapasso F, Henry AC, Dumon KR, Huebner K, Williams NN, Kaiser LR, Croce CM |
| Cancer research. 2003 ; 63 (4) : 878-881. |
| PMID 12591741 |
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| Loss of WWOX expression in gastric carcinoma. |
| Aqeilan RI, Kuroki T, Pekarsky Y, Albagha O, Trapasso F, Baffa R, Huebner K, Edmonds P, Croce CM |
| Clinical cancer research : an official journal of the American Association for Cancer Research. 2004 ; 10 (9) : 3053-3058. |
| PMID 15131042 |
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| Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor. |
| Aqeilan RI, Palamarchuk A, Weigel RJ, Herrero JJ, Pekarsky Y, Croce CM |
| Cancer research. 2004 ; 64 (22) : 8256-8261. |
| PMID 15548692 |
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| Functional association between Wwox tumor suppressor protein and p73, a p53 homolog. |
| Aqeilan RI, Pekarsky Y, Herrero JJ, Palamarchuk A, Letofsky J, Druck T, Trapasso F, Han SY, Melino G, Huebner K, Croce CM |
| Proceedings of the National Academy of Sciences of the United States of America. 2004 ; 101 (13) : 4401-4406. |
| PMID 15070730 |
| |
| The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma. |
| Guler G, Uner A, Guler N, Han SY, Iliopoulos D, Hauck WW, McCue P, Huebner K |
| Cancer. 2004 ; 100 (8) : 1605-1614. |
| PMID 15073846 |
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| The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis. |
| Kuroki T, Yendamuri S, Trapasso F, Matsuyama A, Aqeilan RI, Alder H, Rattan S, Cesari R, Nolli ML, Williams NN, Mori M, Kanematsu T, Croce CM |
| Clinical cancer research : an official journal of the American Association for Cancer Research. 2004 ; 10 (7) : 2459-2465. |
| PMID 15073125 |
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| WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins. |
| Ludes-Meyers JH, Kil H, Bednarek AK, Drake J, Bedford MT, Aldaz CM |
| Oncogene. 2004 ; 23 (29) : 5049-5055. |
| PMID 15064722 |
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| Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma. |
| Park SW, Ludes-Meyers J, Zimonjic DB, Durkin ME, Popescu NC, Aldaz CM |
| British journal of cancer. 2004 ; 91 (4) : 753-759. |
| PMID 15266310 |
| |
| WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function. |
| Aqeilan RI, Donati V, Palamarchuk A, Trapasso F, Kaou M, Pekarsky Y, Sudol M, Croce CM |
| Cancer research. 2005 ; 65 (15) : 6764-6772. |
| PMID 16061658 |
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| WWOX gene restoration prevents lung cancer growth in vitro and in vivo. |
| Fabbri M, Iliopoulos D, Trapasso F, Aqeilan RI, Cimmino A, Zanesi N, Yendamuri S, Han SY, Amadori D, Huebner K, Croce CM |
| Proceedings of the National Academy of Sciences of the United States of America. 2005 ; 102 (43) : 15611-15616. |
| PMID 16223882 |
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| Concordant loss of fragile gene expression early in breast cancer development. |
| Guler G, Uner A, Guler N, Han SY, Iliopoulos D, McCue P, Huebner K |
| Pathology international. 2005 ; 55 (8) : 471-478. |
| PMID 15998374 |
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| Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer. |
| Iliopoulos D, Guler G, Han SY, Johnston D, Druck T, McCorkell KA, Palazzo J, McCue PA, Baffa R, Huebner K |
| Oncogene. 2005 ; 24 (9) : 1625-1633. |
| PMID 15674328 |
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| Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status. |
| Nunez MI, Ludes-Meyers J, Abba MC, Kil H, Abbey NW, Page RE, Sahin A, Klein-Szanto AJ, Aldaz CM |
| Breast cancer research and treatment. 2005 ; 89 (2) : 99-105. |
| PMID 15692750 |
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| Characterization of the linkage disequilibrium structure and identification of tagging-SNPs in five DNA repair genes. |
| Allen-Brady K, Camp NJ |
| BMC cancer. 2005 ; 5 : page 99. |
| PMID 16091150 |
| |
| Deletion and mutation of WWOX exons 6-8 in human non-small cell lung cancer. |
| Zhou Y, Xu Y, Zhang Z |
| Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. 2005 ; 25 (2) : 162-165. |
| PMID 16116962 |
| |
| Physical association with WWOX suppresses c-Jun transcriptional activity. |
| Gaudio E, Palamarchuk A, Palumbo T, Trapasso F, Pekarsky Y, Croce CM, Aqeilan RI |
| Cancer research. 2006 ; 66 (24) : 11585-11589. |
| PMID 17178850 |
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| Roles of FHIT and WWOX fragile genes in cancer. |
| Iliopoulos D, Guler G, Han SY, Druck T, Ottey M, McCorkell KA, Huebner K |
| Cancer letters. 2006 ; 232 (1) : 27-36. |
| PMID 16225988 |
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| PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. |
| Jin C, Ge L, Ding X, Chen Y, Zhu H, Ward T, Wu F, Cao X, Wang Q, Yao X |
| Biochemical and biophysical research communications. 2006 ; 341 (3) : 784-791. |
| PMID 16438931 |
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| Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox. |
| Mahajan NP, Whang YE, Mohler JL, Earp HS |
| Cancer research. 2005 ; 65 (22) : 10514-10523. |
| PMID 16288044 |
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| WWOX protein expression in normal human tissues. |
| Nunez MI, Ludes-Meyers J, Aldaz CM |
| Journal of molecular histology. 2006 ; 37 (3-4) : 115-125. |
| PMID 16941225 |
| |
| Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas. |
| Pimenta FJ, Gomes DA, Perdigˆ£o PF, Barbosa AA, Romano-Silva MA, Gomez MV, Aldaz CM, De Marco L, Gomez RS |
| International journal of cancer. Journal international du cancer. 2006 ; 118 (5) : 1154-1158. |
| PMID 16152610 |
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| WWOX--the FRA16D cancer gene: expression correlation with breast cancer progression and prognosis. |
| P‰Çuciennik E, Kusi‰Ñska R, Potemski P, Kubiak R, Kordek R, Bednarek AK |
| European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2006 ; 32 (2) : 153-157. |
| PMID 16360296 |
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| A role for the WWOX gene in prostate cancer. |
| Qin HR, Iliopoulos D, Semba S, Fabbri M, Druck T, Volinia S, Croce CM, Morrison CD, Klein RD, Huebner K |
| Cancer research. 2006 ; 66 (13) : 6477-6481. |
| PMID 16818616 |
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| Targeted deletion of Wwox reveals a tumor suppressor function. |
| Aqeilan RI, Trapasso F, Hussain S, Costinean S, Marshall D, Pekarsky Y, Hagan JP, Zanesi N, Kaou M, Stein GS, Lian JB, Croce CM |
| Proceedings of the National Academy of Sciences of the United States of America. 2007 ; 104 (10) : 3949-3954. |
| PMID 17360458 |
| |
