Atlas of Genetics and Cytogenetics in Oncology and Haematology


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List of all cancer genes by chromosome

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

- chromosome 16 -
SymbolGoldenPath (Mb)LocationDescription
RHBDF1 48.058 16p13.3 rhomboid 5 homolog 1 (Drosophila)
MPG 68.169 16p13.3 N-methylpurine-DNA glycosylase
RGS11 258.311 16p13.3 regulator of G-protein signaling 11
AXIN1 277.441 16p13.3 axin 1
MRPL28 357.397 16p13.3 mitochondrial ribosomal protein L28
NME4 387.193 16p13.3 non-metastatic cells 4, protein expressed in
PIGQ 560.005 16p13.3 phosphatidylinositol glycan anchor biosynthesis, class Q
RAB40C 580.180 16p13.3 RAB40C, member RAS oncogene family
STUB1 670.116 16p13.3 STIP1 homology and U-box containing protein 1
MSLN 751.134 16p13.3 mesothelin
CHTF18 778.623 16p13.3 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
GNG13 788.042 16p13.3 guanine nucleotide binding protein (G protein), gamma 13
SSTR5 1068.870 16p13.3 somatostatin receptor 5
C1QTNF8 1078.227 16p13.3 C1q and tumor necrosis factor related protein 8
CACNA1H 1143.242 16p13.3 calcium channel, voltage-dependent, T type, alpha 1H subunit
TPSAB1 1230.679 16p13.3 tryptase alpha/beta 1
UBE2I 1299.639 16p13.3 ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
MAPK8IP3 1696.222 16p13.3 mitogen-activated protein kinase 8 interacting protein 3
NME3 1760.322 16q13.3 non-metastatic cells 3, protein expressed in
EME2 1763.230 16p13.3 essential meiotic endonuclease 1 homolog 2 (S. pombe)
IGFALS 1780.420 16p13.3 insulin-like growth factor binding protein, acid labile subunit
HAGH 1799.105 16p13.3 hydroxyacylglutathione hydrolase
SEPX1 1928.235 16p13.3 selenoprotein X, 1
RPS2 1952.063 16p13.3 ribosomal protein S2
GFER 1974.151 16p13.3-p13.12 growth factor, augmenter of liver regeneration
SLC9A3R2 2016.889 16p13.3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
NTHL1 2029.817 16p13.3 nth endonuclease III-like 1 (E. coli)
TSC2 2037.991 16p13.3 tuberous sclerosis 2
PKD1 2078.712 16p13.3 polycystic kidney disease 1 (autosomal dominant)
RAB26 2138.652 16p13.3 RAB26, member RAS oncogene family
TRAF7 2145.800 16p13.3 TNF receptor-associated factor 7
E4F1 2213.568 16p13.3 E4F transcription factor 1
ABCA3 2265.880 16p13.3 ATP-binding cassette, sub-family A (ABC1), member 3
CCNF 2419.396 16p13.3 cyclin F
PDPK1 2527.971 16p13.3 3-phosphoinositide dependent protein kinase-1
TCEB2 2761.416 16p12.3 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
PRSS21 2807.165 16p13.3 protease, serine, 21 (testisin)
PKMYT1 2962.793 16p13.3 protein kinase, membrane associated tyrosine/threonine 1
TNFRSF12A 3010.314 16p13.3 tumor necrosis factor receptor superfamily, member 12A
MMP25 3036.683 16p13.3 matrix metallopeptidase 25
IL32 3055.314 16p13.3 interleukin 32
CLUAP1 3490.964 16p13.3 clusterin associated protein 1
TRAP1 3648.039 16p13.3 TNF receptor-associated protein 1
CREBBP 3715.057 16p13.3 CREB binding protein
Magmas 4330.253 16p13.3 mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction
DNAJA3 4415.883 16p13.3 DnaJ (Hsp40) homolog, subfamily A, member 3
HMOX2 4466.342 16p13.3 heme oxygenase (decycling) 2
C16orf5 4500.678 16p13.3 chromosome 16 open reading frame 5
PPL 4872.509 16p13.3 periplakin
USP7 8893.452 16p13.3 ubiquitin specific peptidase 7 (herpes virus-associated)
GRIN2A 9762.923 16p13.2 glutamate receptor, ionotropic, N-methyl D-aspartate 2A
CIITA 10878.556 16p13 class II, major histocompatibility complex, transactivator
SOCS1 11255.775 16p13.13 suppressor of cytokine signaling 1
PRM2 11276.994 16p13.13 protamine 2
LITAF 11549.357 16p13.3-p12 lipopolysaccharide-induced TNF factor
GSPT1 11869.486 16p13.1 G1 to S phase transition 1
TNFRSF17 11966.465 16p13.1 tumor necrosis factor receptor superfamily, member 17
ERCC4 13921.515 16p13.3|16p13.3-p13.11 excision repair cross-complementing rodent repair deficiency, complementation group 4
MKL2 14072.697 16p13.3 MKL/myocardin-like 2
BFAR 14634.297 16p13.12 bifunctional apoptosis regulator
PLA2G10 14673.906 16p13.1-p12 phospholipase A2, group X
RRN3 15061.380 16p12 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
MYH11 15704.493 16p13.11 myosin, heavy chain 11, smooth muscle
ABCC1 15950.935 16p13.1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC6 16222.545 16p13.1 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
SMG1 18723.676 16p12.3 PI-3-kinase-related kinase SMG-1
C16orf62 19474.541 16p12.3 chromosome 16 open reading frame 62
EEF2K 22125.093 16p12 eukaryotic elongation factor-2 kinase
CDR2 22264.758 16p13.1-p12 cerebellar degeneration-related protein 2, 62kDa
HS3ST2 22733.361 16p12 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
SCNN1B 23221.092 16p12.2-p12.1 sodium channel, nonvoltage-gated 1, beta
PALB2 23521.984 16p12.1 partner and localizer of BRCA2
PLK1 23597.702 16p polo-like kinase 1 (Drosophila)
ERN2 23609.127 16p12.2 endoplasmic reticulum to nucleus signaling 2
CHP2 23673.449 16p12.1 calcineurin B homologous protein 2
PRKCB 23754.823 16p12 protein kinase C, beta
PRKCB1 23754.823 16p12 protein kinase C, beta 1
RBBP6 24458.409 16p12.2 retinoblastoma binding protein 6
ARHGAP17 24838.213 16p12.2-p12.1 Rho GTPase activating protein 17
AQP8 25135.786 16p12 aquaporin 8
NSMCE1 27143.816 16p12.1 non-SMC element 1 homolog (S. cerevisiae)
IL4R 27232.752 16p12.1-p11.2 interleukin 4 receptor
IL21R 27346.080 16p11 interleukin 21 receptor
IL27 28418.184 16p11 interleukin 27
NUPR1 28456.163 16p11.2 nuclear protein 1
SULT1A2 28510.767 16p12.1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT1A1 28524.419 16p12.1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
EIF3C 28630.283 16p11.2 eukaryotic translation initiation factor 3, subunit C
SH2B1 28782.815 16p11.2 SH2B adaptor protein 1
ATP2A1 28797.310 16p12.1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
CD19 28850.761 16p11.2 CD19 molecule
GIYD2 29373.376 16p11.2 GIY-YIG domain containing 2
SPN 29581.801 16p11.2 sialophorin
MAZ 29725.356 16p11.2 MYC-associated zinc finger protein (purine-binding transcription factor)
MVP 29739.288 16p11.2 major vault protein
SEZ6L2 29789.981 16p12.1 seizure related 6 homolog (mouse)-like 2
TAOK2 29892.723 16p11.2 TAO kinase 2
ALDOA 29971.992 16p11.2 aldolase A, fructose-bisphosphate
PPP4C 29994.885 16p12-p11 protein phosphatase 4 (formerly X), catalytic subunit
MAPK3 30032.927 16p11.2 mitogen-activated protein kinase 3
SEPT1 30296.957 16p11.1 septin 1
ITGAL 30391.484 16p11.2 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ZNF689 30522.201 16p11.2 zinc finger protein 689
SRCAP 30617.963 16p11.2 Snf2-related CREBBP activator protein
PHKG2 30667.238 16p11.2 phosphorylase kinase, gamma 2 (testis)
RNF40 30681.131 16p11.2-p11.1 ring finger protein 40
BCL7C 30806.617 16p11 B-cell CLL/lymphoma 7C
CTF1 30815.429 16p11.2 cardiotrophin 1
BCKDK 31027.163 16p11.2 branched chain ketoacid dehydrogenase kinase
MYST1 31036.488 16p11.1 MYST histone acetyltransferase 1
PRSS8 31050.255 16p11.2 protease, serine, 8
FUS 31098.954 16p11.2 fusion (involved in t(12;16) in malignant liposarcoma)
PYCARD 31120.308 16p11.2 PYD and CARD domain containing
PYDC1 31134.784 16p11.2 PYD (pyrin domain) containing 1
ITGAM 31178.789 16p11.2 integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX 31274.010 16p11.2 integrin, alpha X (complement component 3 receptor 4 subunit)
ITGAD 31312.134 16p13.1-p11 integrin, alpha D
COX6A2 31346.556 16p11.12 cytochrome c oxidase subunit VIa polypeptide 2
TGFB1I1 31390.985 16p11 transforming growth factor beta 1 induced transcript 1
SLC5A2 31401.940 16p12-p11 solute carrier family 5 (sodium/glucose cotransporter), member 2
TP53TG3 33112.481 16p13 TP53TG3 protein
ORC6L 45281.059 16q12 origin recognition complex, subunit 6 like (yeast)
DNAJA2 45546.775 16q12.1 DnaJ (Hsp40) homolog, subfamily A, member 2
ABCC11 46758.323 16q12 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
SIAH1 46951.947 16q12 seven in absentia homolog 1 (Drosophila)
ADCY7 48879.324 16q12.1 adenylate cyclase 7
BRD7 48910.442 16q12.1 bromodomain containing 7
NOD2 49288.551 16q12 nucleotide-binding oligomerization domain containing 2
CYLD 49333.462 16q12-q13 cylindromatosis (turban tumor syndrome)
RBL2 52025.852 16q12.2 retinoblastoma-like 2 (p130)
IRX5 53522.612 16q12.2 iroquois homeobox 5
MMP2 54072.975 16q13-q21 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
SLC6A2 54248.057 16q12.2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
CES1 54394.265 16q22.2 carboxylesterase 1 (monocyte/macrophage serine esterase 1)
GNAO1 54782.752 16q13 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
AMFR 54952.865 16q21 autocrine motility factor receptor
MT3 55180.768 16q13 metallothionein 3
MT2A 55200.012 16q13 metallothionein 2A
MT1A 55230.079 16q13 metallothionein 1A
MT1F 55249.356 16q13 metallothionein 1F
MT1G 55258.154 16q13 metallothionein 1G
MT1H 55261.227 16q13 metallothionein 1H
NUP93 55321.608 16q13 nucleoporin 93kDa
SLC12A3 55456.620 16q13 solute carrier family 12 (sodium/chloride transporters), member 3
CCL22 55950.219 16q13 chemokine (C-C motif) ligand 22
CX3CL1 55963.915 16q13 chemokine (C-X3-C motif) ligand 1
CCL17 55996.180 16q13 chemokine (C-C motif) ligand 17
CIAPIN1 56019.588 16q13-q21 cytokine induced apoptosis inhibitor 1
GPR56 56211.459 16q12.2-q21 G protein-coupled receptor 56
MMP15 56616.783 16q13 matrix metallopeptidase 15 (membrane-inserted)
CSNK2A2 56749.313 16 casein kinase 2, alpha prime polypeptide
NDRG4 57055.495 16q21-q22.3 NDRG family member 4
CDH8 60244.736 16q22.1 cadherin 8, type 2
CDH11 63538.184 16q21 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH5 64958.026 16q22.1 cadherin 5, type 2 (vascular endothelium)
TK2 65100.846 16 thymidine kinase 2, mitochondrial
CDH16 65499.526 16q22.1 cadherin 16, KSP-cadherin
RRAD 65513.083 16q22 Ras-related associated with diabetes
CES2 65525.848 16q22.1 carboxylesterase 2 (intestine, liver)
CBFB 65620.551 16q22.1 core-binding factor, beta subunit
TRADD 65745.590 16q22 TNFRSF1A-associated via death domain
NOL3 65765.371 16q22.1 nucleolar protein 3 (apoptosis repressor with CARD domain)
E2F4 65783.569 16q21-q22 E2F transcription factor 4, p107/p130-binding
HSD11B2 66022.537 16q22 hydroxysteroid (11-beta) dehydrogenase 2
CTCF 66153.965 16q21-q22.3 CCCTC-binding factor (zinc finger protein)
ACD 66248.916 16q22 adrenocortical dysplasia homolog (mouse)
PSKH1 66484.676 16q22.1 protein serine kinase H1
PSMB10 66525.908 16q22.1 proteasome (prosome, macropain) subunit, beta type, 10
LCAT 66531.288 16q22.1 lecithin-cholesterol acyltransferase
SLC12A4 66535.731 16q22.1 solute carrier family 12 (potassium/chloride transporters), member 4
DDX28 66612.675 16q22.1-q22.3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
NFATC3 66676.876 16q22 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
SMPD3 66949.731 16q22.1 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
CDH3 67235.652 16q22.1 cadherin 3, type 1, P-cadherin (placental)
CDH1 67328.696 16q22.1 cadherin 1, type 1, E-cadherin (epithelial)
HAS3 67698.944 16q22.1 hyaluronan synthase 3
CTF8 67709.414 16q22.1 chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
PDF 67920.025 16q22.1 peptide deformylase (mitochondrial)
TERF2 67947.034 16q22.1 telomeric repeat binding factor 2
NFAT5 68156.498 16q22.1 nuclear factor of activated T-cells 5, tonicity-responsive
NQO1 68300.805 16q12-q22 NAD(P)H dehydrogenase, quinone 1
WWP2 68353.775 16q22.1 WW domain containing E3 ubiquitin protein ligase 2
DDX19B 68890.573 16q22.3 DEAD (Asp-Glu-Ala-As) box polypeptide 19B
DDX19A 68938.325 16q22.1 DEAD (Asp-Glu-Ala-As) box polypeptide 19A
FUK 69045.999 16q22.1 fucokinase
SF3B3 69115.202 16q22.1 splicing factor 3b, subunit 3, 130kDa
VAC14 69278.843 16q22.1 Vac14 homolog (S. cerevisiae)
HYDIN 69618.512 16q22.2 hydrocephalus inducing homolog (mouse)
CALB2 69950.127 16q22.2 calbindin 2
ZNF23 70039.004 16q22 zinc finger protein 23 (KOX 16)
CHST4 70117.562 16q22.2 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
TAT 70158.255 16q22.1 tyrosine aminotransferase
DHODH 70600.144 16q22 dihydroorotate dehydrogenase
HP 70646.009 16q22.1 haptoglobin
DHX38 70685.116 16q22 DEAH (Asp-Glu-Ala-His) box polypeptide 38
ZFHX3 71374.287 16q22.3 zinc finger homeobox 3
PSMD7 72888.182 16q22.3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
GLG1 73043.357 16q22-q23 golgi apparatus protein 1
MLKL 73263.262 16q22.3 mixed lineage kinase domain-like
FA2H 73304.359 16q23 fatty acid 2-hydroxylase
BCAR1 73820.429 16q22-q23 breast cancer anti-estrogen resistance 1
CFDP1 73885.109 16q22.2-q22.3 craniofacial development protein 1
TERF2IP 74239.185 16q22.3 telomeric repeat binding factor 2, interacting protein
ADAMTS18 75873.526 16q23 ADAM metallopeptidase with thrombospondin type 1 motif, 18
WWOX 76691.052 16q23.3-q24.1 WW domain containing oxidoreductase
MAF 78185.732 16q22-q23 v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
DYNLRB2 79132.355 16q23.3 dynein, light chain, roadblock-type 2
ATMIN 79626.959 16q23.2 ATM interactor
PLCG2 80370.431 16q24.1 phospholipase C, gamma 2 (phosphatidylinositol-specific)
HSD17B2 80626.364 16q24.1-q24.2 hydroxysteroid (17-beta) dehydrogenase 2
CDH13 81218.079 16q23.3 cadherin 13, H-cadherin (heart)
OSGIN1 82540.173 16q23.3 oxidative stress induced growth inhibitor 1
MBTPS1 82644.870 16q24 membrane-bound transcription factor peptidase, site 1
WFDC1 82885.902 16q24.3 WAP four-disulfide core domain 1
COTL1 83156.705 16q24.1 coactosin-like 1 (Dictyostelium)
COX4I1 84390.697 16q22-qter cytochrome c oxidase subunit IV isoform 1
IRF8 84490.275 16q24.1 interferon regulatory factor 8
FOXF1 85101.634 16q24 forkhead box F1
FOXC2 85158.443 16q24.1 forkhead box C2 (MFH-1, mesenchyme forkhead 1)
FOXL1 85169.616 16q24 forkhead box L1
FBXO31 85920.443 16q24 F-box protein 31
SLC7A5 86421.130 16q24.3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
IL17C 87232.502 16q24 interleukin 17C
CYBA 87237.198 16q24 cytochrome b-245, alpha polypeptide
RNF166 87290.410 16q24.3 ring finger protein 166
FAM38A 87309.513 16q24.3 family with sequence similarity 38, member A
CDT1 87397.687 16q24.3 chromatin licensing and DNA replication factor 1
APRT 87403.378 16q24 adenine phosphoribosyltransferase
CBFA2T3 87468.768 16q24 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CDH15 87765.664 16q24.3 cadherin 15, M-cadherin (myotubule)
ANKRD11 87861.536 16q24.3 ankyrin repeat domain 11
SPG7 88102.306 16q24.3 spastic paraplegia 7 (pure and complicated autosomal recessive)
RPL13 88154.591 16q24.3 ribosomal protein L13
CPNE7 88169.677 16q24.3 copine VII
DPEP1 88207.217 16q24 dipeptidase 1 (renal)
CDK10 88280.579 16q24.3 cyclin-dependent kinase 10
FANCA 88331.460 16q24.3 Fanconi anemia, complementation group A
TCF25 88467.527 16q24.3 transcription factor 25 (basic helix-loop-helix)
MC1R 88511.788 16q24.3 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
TUBB3 88517.246 16q24.3 tubulin, beta 3
GAS8 88616.509 16q24.3 growth arrest-specific 8
PRDM7 88650.475 16q24.3 PR domain containing 7


These entries belong to a list of genes implicated in cancer which is a compilation of genes
from Atlas of Genetics and Cytogenetics and some other genes selected for their interest.


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