Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Chromosome 2

Chromosome 2 : G-banding, diagram and R-banding - Claude Léonard, Jean-Loup Huret

Leukaemia     

t(1;2)(q25;p23)
t(1;2)(q12;q37)
inv(2)(p23q35)
Trisomy 2
t(2;3)(p23;q21)
t(2;3)(p15-23;q26-27)
t(2;3)(p12;q27)
t(2;4)(p23;q25-q35)
t(2;5)(p23;q35)
t(2;8)(p12;q24)
t(2;9)(p11;p13)
t(2;11)(p21;q23)
t(2;11)(q11;q23)
t(2;11)(q31;p15) (MDS, AML; NUP98 and HOXD13; rare)
t(2;11)(q31;p15) (MDS, AML; NUP98 and HOXD11; rare)
t(2;11)(q37;q23) (AML; SEPT2 and MLL; rare)
t(2;11)(q37;q23) in AML
t(2;12)(q31;p13)
t(2;13)(p16;q12)
t(2;14)(p13;q32)
t(2;17)(p23;q23)
t(2;17)(p23;q25)
t(2;18)(p11;q21)
t(2;19)(p11;p13)
t(2;21)(p11;q22)
t(2;22)(p13;q11) (NHL; REL and IgL; rare)
t(2;22)(p23;q11.2)
t(2;22)(p23;q11.2)
t(X;2)(q11;p23)

Solid Tumors     

t(1;2)(q25;p23)
t(1;2)(q25;p23)
t(1;2)(q25;p23)
t(2;2)(p23;q13)
t(2;2)(p23;q13)
t(2;11)(p23;p15)
t(2;11)(p23;p15)
t(2;13)(q35;q14)
t(2;13)(q35;q14)
t(2;17)(p23;q23)
t(2;17)(p23;q23)
t(2;19)(p23;p13)
t(2;19)(p23;p13.1)
t(2;19)(p23;p13.1)
t(2;22)(q23;q12)

Cancer prone diseases     

Carney complex (CNC)
Familial clear cell renal cancer
Hereditary non polyposis colorectal carcinoma (HNPCC Syndrome)
Hereditary Pancreatic Cancer
Trichothiodystrophy (TTD)
Waardenburg syndrome (WS)
Xeroderma pigmentosum

All Genes by Location (Kb)
Chromosome 2 by location

Losses / Amplicons     

BONE/SOFT TISSUE

External links     

  • Chromosome 2 - HUGO Chromosomes
  • Chromosome 2 - GoldenPath - Santa Cruz
  • Chromosome 2 - Ensembl Project
  • Chromosome 2 - Map View - NCBI
  • Chromosome 2 - GDB (Genome Data Base)
  • Chromosome 2 - OMIM Gene map
  • Chromosome 2 - Genomic Variants
  • Chromosome 2 - HAPMAP Project
  • Chromosome 2 - Genome Channel - ORNL
  • Chromosome 2 - LaunchPad HGMIS
  • Chromosome 2 - Human Protein Atlas
  • Chromosome 2 - SpliceNest
  • Human BAC Resource (NCBI)
  • FISH-mapped BACs (CCAP)
  • Genetic Maps (CHLC)
  • YACs mapped by FISH (Bari)
  • PCP (Partial Chromosome Paints) (Bari)
  • Positional Cloning Project (Berlin Dahlem)
  • Mouse homology - OMIM - NCBI
  • Cancer GeneWeb
  • GeneCards (Weizmann)
  • IMGT, the international ImMunoGeneTics database (Montpellier,France)
  • Human Proteomics Initiative (Expasy)

    • Genes

    Annotated genes
    Ordered by Name Ordered by Location
     Kb pter-qter
    E2F6 11501.953 2p25.1
    MYCN 15998.134 2p24.3
    SDC1 20264.041 2p24.1
    RHOB 20510.316 2p24
    ALK 29269.146 2p23
    NLRC4 32303.024 2p22-p21
    BIRC6 32435.600 2p22.3
    TACSTD1 47449.971 2p21
    MSH2 47483.767 2p21
    MSH6 47863.725 2p16
    LHCGR 48767.425 2p21
    RTN4 55052.833 2p14-p13
    BCL11A 60537.833 2p16.1
    REL 60962.256 2p13-p12
    IGK@ 88937.794 2p12
    AFF3 99530.150 2q11.2-q12
    MAP4K4 101680.920 2q11.2-q12
    RANBP2 108702.369 2q13
    IL1B 113303.808 2q14
    ERCC3 127731.336 2q21
    ACVR2A 148319.040 2q22.2-q23.3
    ATF2 175647.254 2q32
    DIRC1 189306.710 2q33
    HSPD1 198059.555 2q33.1
    ADAM23 207016.613 2q33
    IKZF2 213572.658 2q13.1
    BARD1 215301.520 2q34-q35
    ATIC 215885.081 2q35
    DIRC3 217856.992 2q35
    CXCR7 237143.119 2q37.3
    SEPT2 241903.954 2q37.3
    BOK 242146.865 2q37.3
    Other genes
    possibly implicated
    in cancer
    Ordered by Name Ordered by Location
     Kb pter-qter
    ACP1 254.896 2p25
    TPO 1396.242 2p25
    PXDN 1614.667 2p25.3
    TSSC1 3171.750 2p25.3
    ADI1 3480.698 2p25.2
    SOX11 5750.250 2p25
    RNF144A 6974.974 2p25.2
    ID2 8739.564 2p25
    KIDINS220 8786.511 2p24
    ITGB1BP1 9463.274 2p25.2
    ADAM17 9546.864 2p25
    YWHAQ 9641.558 2p25.2-p25.1
    TAF1B 9901.024 2p25
    UNQ5830 10060.736 2p25.1
    RRM2 10180.186 2p25-p24
    ODC1 10497.959 2p25
    ROCK2 11239.229 2p24
    GREB1 11600.302 2p25.1
    TRIB2 12774.659 2p25.1
    FAM84A 14690.307 2p24.3
    NAG 15224.483 2p24
    DDX1 15649.221 2p24
    MYCNOS 15993.837 2p24.1
    VSNL1 17585.288 2p24.3
    SMC6 17708.562 2p24.3
    GEN1 17798.661 2p24.2
    OSR1 19414.728 2p24.1
    PUM2 20311.934 2p22-p21
    GDF7 20729.905 2p24.1
    APOB 21077.807 2p24-p23
    TP53I3 24153.810 2p23.3
    ITSN2 24279.240 2pter-p25.1
    NCOA1 24660.850 2p23
    RBJ 25020.009 2p23.3
    POMC 25237.226 2p23
    DNMT3A 25309.350 2p23
    RAB10 26110.478 2p23.3
    CIB4 26657.577 2p23.3
    CENPA 26862.386 2p24-p21
    DPYSL5 26924.467 2p23.3
    MAPRE3 27047.029 2p23.3-p23.1
    KHK 27163.115 2p23.3-p23.2
    CAD 27293.762 2p22-p21
    DNAJC5G 27351.793 2p23
    TRIM54 27359.104 2p23.3
    UCN 27383.769 2p23-p21
    PPM1G 27457.566 2p23.3
    NRBP1 27504.977 2p23
    GCKR 27573.210 2p23
    XAB1 27705.407 2p23.3
    SUPT7L 27727.183 2p23.3
    BRE 27967.061 2p23
    FOSL2 28469.283 2p23.3
    PPP1CB 28828.118 2p23
    XDH 31410.692 2p23.1
    SRD5A2 31603.160 2p23.1
    LTBP1 33025.896 2p22-p21
    RASGRP3 33514.920 2p25.1-p24.1
    CRIM1 36436.901 2p21
    EIF2AK2 37187.203 2p22-p21
    PRKD3 37331.152 2p21
    CDC42EP3 37724.247 2p21
    CYP1B1 38148.250 2p22.2
    GEMIN6 38858.831 2p22.1
    DHX57 38878.379 2p22.3
    SOS1 39066.470 2p21
    CDKL4 39259.194 2p22.3
    MAP4K3 39329.927 2p22.3
    EML4 42250.020 2p21
    COX7A2L 42431.148 2p21
    MTA3 42649.175 2p22.1
    OXER1 42843.146 2p22.1
    THADA 43311.479 2p21
    PPM1B 44249.504 2p22.1
    PREPL 44399.407 2p22.1
    SIX3 45022.541 2p21
    PRKCE 45732.547 2p21
    EPAS1 46378.067 2p21-p16
    RHOQ 46623.371 2p21
    PIGF 46661.918 2p21-p16
    FOXN2 48395.299 2p22-p16
    FSHR 49043.157 2p21-p16
    PSME4 53944.708 2p16.1
    ACYP2 54195.914 2p16.2
    SPTBN1 54639.035 2p21
    RPS27A 55313.328 2p16
    CCDC88A 55368.484 2p16.3
    SMEK2 55629.019 2p16.1
    PNPT1 55715.971 2p15
    EFEMP1 55946.606 2p16
    VRK2 58127.224 2p16.1
    FANCL 58239.882 2p16.1
    AHSA2 61258.325 2p14
    XPO1 61558.574 2p15
    B3GNT2 62276.766 2p15
    MDH1 63669.626 2p23
    VPS54 63973.172 2p15-p14
    PELI1 64173.500 2p13.3
    RAB1A 65167.493 2p14
    ACTR2 65308.406 2p14
    SPRED2 65391.490 2p14
    MEIS1 66516.036 2p14
    ETAA1 67477.946 2p14
    C1D 68122.842 2p13-p12
    PPP3R1 68259.493 2p16-p15
    PLEK 68445.826 2p13.3
    C2orf13 68548.246 2
    ARHGAP25 68855.437 2p13.3
    BMP10 68946.117 2p13.2
    GKN2 69025.869 2p14
    GKN1 69055.209 2p13.3
    ANTXR1 69093.993 2p13.1
    AAK1 69538.631 2p24.3-p14
    ANXA4 69822.631 2p13.3
    MXD1 69995.707 2p13-p12
    ASPRV1 70040.730 2p13.3
    PCBP1 70168.205 2p13-p12
    TIA1 70292.320 2p13
    TGFA 70527.925 2p13
    DYSF 71534.268 2p13.3
    SMYD5 73294.874 2p12
    TET3 74126.958 2p13.1
    MOBKL1B 74236.719 2p13.1
    RTKN 74506.497 2p13.1
    ZNHIT4 74535.707 2p13.1
    PCGF1 74585.686 2p13.1
    TLX2 74595.119 2p13.1
    HTRA2 74610.040 2p13.1
    LOXL3 74613.454 2p13
    DOK1 74635.368 2p13
    SEMA4F 74734.901 2p13.1
    HK2 74913.290 2p13
    POLE4 75039.283 2p12
    TACR1 75131.672 2p13.1-p12
    REG1A 79201.092 2p12
    REG3A 79237.641 2p12
    TMSB10 84986.274 2p11.2
    KCMF1 85051.742 2p11.2
    TCF7L1 85214.245 2p11.2
    CAPG 85475.382 2p11.2
    MAT2A 85619.799 2p11.2
    GNLY 85774.925 2p12-q11
    JMJD1A 86521.865 2p11.2
    VPS24 86584.065 2p24.3-p24.1
    RNF103 86684.027 2p11.2
    CD8A 86865.240 2p12
    CD8B 86922.201 2p12
    SMYD1 88148.497 2p11.1
    EIF2AK3 88637.374 2p12
    MAL 95055.206 2cen-q13
    PROM2 95303.928 2q11.1
    KCNIP3 95326.799 2q21.1
    ADRA2B 96142.353 2p13-q13
    DUSP2 96172.644 2q11
    CIAO1 96295.611 2q11.1-q11.2
    NCAPH 96365.211 2q11.2
    ANKRD36B 97487.693 2q11.2
    COX5B 97628.953 2cen-q13
    ACTR1B 97638.863 2q11.1-q11.2
    ZAP70 97717.301 2q11-q13
    INPP4A 98427.845 2q11.2
    MGAT4A 98602.003 2q12
    TSGA10 98980.787 2q11.2
    REV1 99383.371 2q11.1-q11.2
    NPAS2 100803.045 2q11.2
    C2orf29 101235.810 2q12.1
    RNF149 101258.985 2q12.1
    IL1R2 101981.891 2q12-q22
    IL1R1 102136.834 2q12
    IL1RL1 102294.394 2q12
    IL18R1 102345.529 2q12
    TGFBRAP1 105249.974 2q12.1
    FHL2 105343.717 2q12.2
    C2orf40 106048.545 2q12.2
    LIMS1 108571.199 2q12.3
    SEPT10 109657.665 2q13
    BUB1 111111.883 2p11-q21
    BCL2L11 111594.962 2q13
    ANAPC1 112243.113 2q12.1
    MERTK 112372.662 2q14.1
    TTL 112956.214 2q13
    POLR1B 113016.084 2q13
    SLC20A1 113119.998 2q11-q14
    IL1A 113247.964 2q14
    IL1F7 113387.019 2q12-q14.1
    IL1F9 113452.077 2q12-q21
    IL1RN 113591.941 2q14.2
    PSD4 113648.031 2q13
    PAX8 113690.045 2q13
    FOXD4L1 113973.131 2q14.1
    RABL2A 114101.354 2q13
    ACTR3 114364.007 2q14.1
    DDX18 118288.725 2q21.2
    INSIG2 118562.520 2q14.1
    EN1 119316.217 2q14.2
    DBI 119841.721 2q12-q21
    SCTR 119913.889 2q14.1
    PTPN4 120233.677 2q14.2
    RALB 120726.884 2cen-q13
    INHBB 120820.189 2cen-q13
    GLI2 121266.327 2q14
    TSN 122229.591 2q21.1
    CNTNAP5 124499.334 2q14.1
    BIN1 127522.079 2q14
    MAP3K2 127778.609 2q21.1
    PROC 127892.487 2q13-q14
    LIMS2 128112.471 2q21.1
    WDR33 128209.432 2q21.1
    POLR2D 128320.705 2q21
    RAB6C 130453.705 2q21.1
    PTPN18 130830.088 2q21
    ARHGEF4 131390.694 2q22
    LOC150786 131834.536 2q21.1
    GPR39 132890.617 2q21-q22
    MGAT5 134728.300 2q21
    CCNT2 135392.863 2q21.3
    YSK4 135438.743 2q21.3
    LCT 136261.885 2q21
    MCM6 136313.674 2q14-q21
    CXCR4 136588.390 2q21
    LRP1B 140705.466 2q21.2
    ARHGAP15 143603.433 2q22.2-q22.3
    ZEB2 144862.054 2q22.3
    ORC4L 148408.203 2q22-q23
    EPC2 149119.038 2q23
    C2orf25 150134.398 2q23
    RND3 151032.955 2q23.3
    NMI 151835.231 2q23
    TNFAIP6 151922.351 2q23.3
    NEB 152050.101 2q22
    RPRM 154042.098 2q24.1
    KCNJ3 155263.339 2q24.1
    NR4A2 156889.197 2q22-q23
    GPD2 157000.211 2q24.1
    ACVR1C 158091.525 2q24.2
    ACVR1 158301.205 2q23-q24
    BAZ2B 159883.738 2q24.2
    CD302 160333.610 2q24.2
    LY75 160368.114 2q24
    ITGB6 160666.480 2q24.2
    C2orf12 160836.908 2q24.3
    RBMS1 160838.761 2q24.2
    TANK 161701.712 2q24-q31
    SLC4A10 162189.091 2q23-q24
    DPP4 162557.003 2q24.3
    GCG 162707.635 2q36-q37
    FAP 162735.448 2q23
    IFIH1 162831.836 2q24.2
    GRB14 165057.579 2q22-q24
    GALNT3 166312.559 2q24-q31
    SCN1A 166553.917 2q24.3
    SCN9A 166759.943 2q24
    STK39 168518.777 2q24.3
    NOSTRIN 169367.353 2q31.1
    ABCB11 169487.695 2q24
    LRP2 169691.865 2q24-q31
    KBTBD10 170074.458 2p14-q14.3
    SSB 170363.635 2q31.1
    MYO3B 170742.901 2q31.1-q31.2
    SP5 171280.107 2q31
    TLK1 171556.816 2q31.1
    HAT1 172487.204 2q31.2-q33.1
    MAP1D 172573.050 2q31.1
    ITGA6 173000.560 2q31.1
    PDK1 173129.025 2q31.1
    ZAK 173648.811 2q24.2
    CDCA7 173927.807 2q31.1
    SP3 174481.505 2q31
    CHN1 175372.338 2q31-q32.1
    HOXD13 176665.778 2q31.1
    HOXD11 176680.330 2q31.1
    HOXD9 176695.334 2q31.1
    HOXD3 176737.051 2q31.1
    NFE2L2 177803.279 2q31
    DFNB59 179026.351 2q31.2
    PLEKHA3 179053.445 2q31.2
    TTN 179098.966 2q31
    SESTD1 179681.776 2q31.3
    UBE2E3 181553.357 2q31.3
    ITGA4 182029.864 2q31.3
    NEUROD1 182249.439 2q32
    SSFA2 182464.927 2q32.1
    PPP1R1C 182558.796 2q31.3
    DNAJC10 183289.244 2q32.1
    FRZB 183406.982 2qter
    ITGAV 187163.045 2q31-q32
    TFPI 188037.205 2q32
    COL3A1 189547.344 2q32.2
    MSTN 190628.671 2q32.1
    INPP1 190916.680 2q32
    NAB1 191222.093 2q32.3-q33
    GLS 191453.792 2q32-q34
    STAT1 191548.510 2q32.2-q32.3
    STAT4 191602.551 2q32.2-q32.3
    TMEFF2 192522.994 2q32.3
    PCGEM1 193322.815 2q32.3
    STK17B 196710.103 2q33.1
    HECW2 196772.222 2q32.3
    ANKRD44 197567.495 2q33.1
    HSPE1 198073.365 2q33.1
    PLCL1 198539.545 2q33
    SATB2 199842.469 2q33.1
    CLK1 201425.978 2q33
    ORC2L 201483.140 2q33
    CASP10 201755.866 2q33-q34
    CASP8 201830.999 2q33-q34
    ALS2CR2 202024.637 2q33.1
    ALS2 202273.522 2q33-q35
    PFTK2 202379.443 2q33.2
    FZD7 202607.555 2q33
    SUMO1 202779.148 2q33
    BMPR2 202949.916 2q33-q34
    ABI2 203901.248 2
    RAPH1 204006.786 2q33
    CD28 204279.443 2q33
    CTLA4 204440.754 2q33
    NRP2 206255.469 2q33.3
    EEF1B2 206732.563 2q33.3
    CREB1 208102.931 2q34
    FAM119A 208185.086 2q33.3
    FZD5 208335.557 2q33-q34
    IDH1 208809.199 2q32-qter
    PIP5K3 208839.236 2q34
    MAP2 210152.648 2q34-q35
    MYL1 210863.114 2q33-q34
    LANCL1 211004.221 2q33-q35
    ERBB4 211948.687 2q33.3-q34
    ABCA12 215504.512 2q34
    FN1 215987.630 2q34
    XRCC5 216682.377 2q35
    SMARCAL1 216986.823 2q35
    IGFBP2 217206.372 2q33-q34
    IGFBP5 217245.074 2q33-q36
    TNP1 217432.427 2q35-q36
    TNS1 218372.757 2q35-q36
    IL8RB 218698.991 2q35
    IL8RA 218735.815 2q35
    ARPC2 218790.119 2q36.1
    GPBAR1 218833.983 2q35
    AAMP 218837.097 2q
    SLC11A1 218954.996 2q35
    PLCD4 219180.876 2q35
    BCS1L 219232.623 2q35
    RNF25 219236.832 2q35
    STK36 219245.053 2q35
    PRKAG3 219395.350 2
    WNT6 219432.790 2q35
    WNT10A 219453.499 2q35
    CDK5R2 219532.642 2q35
    FEV 219554.053 2q36
    IHH 219627.391 2q33-q35
    NHEJ1 219648.292 2q35
    ABCB6 219782.738 2q36
    STK16 219818.468 2q35
    TUBA4A 219823.245 2q36.1
    DNAJB2 219852.284 2q32-q34
    PTPRN 219862.591 2q35-q36.1
    INHA 220145.198 2q33-q36
    STK11IP 220170.840 2q35
    EPHA4 221990.993 2q36.3
    ACSL3 223433.976 2q34-q35
    SCG2 224169.904 2q35-q36
    WDFY1 224448.310 2q36.2
    SERPINE2 224548.122 2q33-q35
    CUL3 225043.113 2q36.2
    KIAA1486 225973.846 2q36.3
    IRS1 227308.182 2q36
    COL4A3 227737.525 2q36-q37
    SLC19A3 228258.171 2q37
    CCL20 228386.814 2q33-q37
    SPHKAP 228552.919 2q36.3
    SP100 230989.115 2q37.1
    CAB39 231285.909 2q37.1
    ARMC9 231771.586 2q37.1
    NCL 232027.704 2q12-qter
    PTMA 232281.479 2q37.1
    PTMAP7 232281.660 14q32
    COPS7B 232359.406 2q37.1
    ALPPL2 232979.796 2q37
    ALPI 233029.077 2q37.1
    NGEF 233451.640 2q37
    INPP5D 233633.280 2q37.1
    SAG 233881.207 2q37.1
    UGT1A10 234209.862 2q37
    UGT1A9 234245.283 2q37
    UGT1A7 234255.323 2q37
    UGT1A6 234265.060 2q37
    UGT1A1 234333.658 2q37
    HJURP 234410.226 2q37.1
    TRPM8