CASE REPORTS in HAEMATOLOGY (Paper co-edited with the European LeukemiaNet)

Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 2

WARNING: on Feb 2008, we have been aware that this case had simultaneously been published in another Journal (namely Cancer Genet Cytogenet), although double reports are objectionable.

Kavita S Reddy, Kathy Richkind

Clinics

Age and sex :	61 year(s) old female patient.
Organomegaly :	no hepatomegaly ; no splenomegaly ; no enlarged lymph nodes ; no central nervous system involvement

Blood

WBC : 3.05 x 109/l; Hb : 8.1 g/dl; platelets : 62 x 109/l;

Cyto pathology classification

Precise diagnosis : Myelofibrosis -> acute leukemia

Survival

Treatment : Induction treatment: topotecan and cytarabine

Relapse : -

Status : Alive

Survival : 55 month(s)

Karyotype

Sample : PB ; culture time : 24/48 h, unstimulated cultures ; banding : G-banding

Results : 46,X,t(X;20)(q13;q13.3),der(1;7)(q10;p10)[20]/46,XX[1]

Fig. 1. Partial karyotypes of the translocation t(X;20)(q13;q13.3) for cases 1•4 (top to bottom). Arrows indicate the derivatives 20 and X.

Internal links

Atlas Card	t(X;20)(q13;q13)
Case Report	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 1
Case Report	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 3
Case Report	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 4

Bibliography

Biclonal acute monoblastic leukemia showing del(7q) and trisomies 9 and 22.

Wong KF, Kwong YL, Tang KC

Cancer genetics and cytogenetics. 1995 ; 82 (1) : 70-72.

PMID 7627939

Translocation (X;20)(q13.1;q13.3) as a primary chromosomal finding in two patients with myelocytic disorders.

Gray BA, Cornfield D, Bent-Williams A, Zori RT

Cancer genetics and cytogenetics. 2003 ; 141 (2) : 169-174.

PMID 12606138

Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders.

Reddy KS, Richkind K, Ross M, Seirra R

Cancer genetics and cytogenetics. 2005 ; 157 (1) : 70-73.

PMID 15676151

Contributor(s)

Written

01-2005

Kavita S Reddy, Kathy Richkind

Citation

This paper should be referenced as such :

Reddy KS, Richkind KE . Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 2. Atlas Genet Cytogenet Oncol Haematol. January 2005 . URL : http://AtlasGeneticsOncology.org/Reports/0X20ReddyID100010.html

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indexed on : Wed Sep 24 21:09:48 2008

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