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del(3)(q27q28) LPP/BCL6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3369
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Diffuse large B-cell lymphoma

Genes involved and Proteins

Gene NameLPP
Location 3q28
Gene NameBCL6
Location 3q27.3

Bibliography

Chromosomal translocations fusing the BCL6 gene to different partner loci are recurrent in primary central nervous system lymphoma and may be associated with aberrant somatic hypermutation or defective class switch recombination
Schwindt H, Akasaka T, Zühlke-Jenisch R, Hans V, Schaller C, Klapper W, Dyer MJ, Siebert R, Deckert M
J Neuropathol Exp Neurol 2006 Aug;65(8):776-82
PMID 16896311
 


Translocations implicated (Data extracted from papers in the Atlas)

 del(3)(q27q28) LPP/BCL6

External links

LPP (3q28) BCL6 (3q27.3)

Mitelman databasedel(3)(q27q28) [Case List]    del(3)(q27q28) [Transloc-MCList] LPP/BCL6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:18:27 CEST 2018


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jlhuret@AtlasGeneticsOncology.org.