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dic(9;20)(p13;q11) PAX5/KIF3B

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2151
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NamePAX5
Location 9p13.2
Gene NameKIF3B
Location 20q11.21

Bibliography

Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer
An Q, Wright SL, Konn ZJ, Matheson E, Minto L, Moorman AV, Parker H, Griffiths M, Ross FM, Davies T, Hall AG, Harrison CJ, Irving JA, Strefford JC
Proc Natl Acad Sci U S A 2008 Nov 4;105(44):17050-4
PMID 18957548
 


Translocations implicated (Data extracted from papers in the Atlas)

 dic(9;20)(p13;q11) PAX5/KIF3B

External links

PAX5 (9p13.2) KIF3B (20q11.21)

Mitelman databasedic(9;20)(p13;q11) [Case List]    dic(9;20)(p13;q11) [Transloc-MCList] PAX5/KIF3B [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Nov 6 14:04:28 CET 2018


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