Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ins(3;7)(q26;q34q22) TRB/MECOM

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Atlas_Id 3290
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloblastic leukemia with minimal differentiation (FAB type M0)

Genes involved and Proteins

Gene NameTRB
Location 7q34
Gene NameMECOM
Location 3q26.2


Activation of EVI1 transcripts with chromosomal translocation joining the TCRVbeta locus and the EVI1 gene in human acute undifferentiated leukemia cell line (Kasumi-3) with a complex translocation of der(3)t(3;7;8)
Suzukawa K, Kodera T, Shimizu S, Nagasawa T, Asou H, Kamada N, Taniwaki M, Yokota J, Morishita K
Leukemia 1999 Sep;13(9):1359-66
PMID 10482986

Translocations implicated (Data extracted from papers in the Atlas)

 ins(3;7)(q26;q34q22) TRB/MECOM

External links

TRB (7q34) MECOM (3q26.2)

Mitelman databaseins(3;7)(q26;q34q22)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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