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ins(4;11)(q21;q23q23) AFF1/DSCAML1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2512
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameAFF1
Location 4q21.3
Gene NameDSCAML1
Location 11q23.3

Bibliography

Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4
Kowarz E, Burmeister T, Lo Nigro L, Jansen MW, Delabesse E, Klingebiel T, Dingermann T, Meyer C, Marschalek R
MLL fusion allele Leukemia
PMID 17410185
 


Translocations implicated (Data extracted from papers in the Atlas)

 ins(4;11)(q21;q23q23) AFF1/DSCAML1

External links

AFF1 (4q21.3) DSCAML1 (11q23.3)

Mitelman databaseins(4;11)(q21;q23q23) [Case List]    ins(4;11)(q21;q23q23) [Transloc-MCList] AFF1/DSCAML1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:19:55 CET 2018


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