ins(4;11)(q21;q23q23) AFF1/DSCAML1

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
AFF1
Location
4q21.3
Gene name
DSCAML1
Location
11q23.3

Bibliography

Pubmed IDLast YearTitleAuthors
174101852007Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4.MLL fusion allele.Kowarz E et al

Summary

Fusion gene

AFF1/DSCAML1 AFF1 (4q21.3) DSCAML1 (11q23.3)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

ins(4;11)(q21;q23q23) AFF1/DSCAML1

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2512/ins(4;11)(q21;q23q23)-aff1-dscaml1