Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 2513 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
Genes involved and Proteins |
Gene Name | AFF1 |
Location | 4q21.3 |
Gene Name | FXYD6 |
Location | 11q23.3 |
Bibliography |
Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4 |
Kowarz E, Burmeister T, Lo Nigro L, Jansen MW, Delabesse E, Klingebiel T, Dingermann T, Meyer C, Marschalek R |
MLL fusion allele Leukemia |
PMID 17410185 |
Translocations implicated (Data extracted from papers in the Atlas) |
ins(4;11)(q21;q23q23) AFF1/FXYD6 | |
External links |
Mitelman database | ins(4;11)(q21;q23q23) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:26:54 CET 2020 |
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