ins(4;11)(q21;q23q23) AFF1/FXYD6

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	2513
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene Name	AFF1
Location	4q21.3

Gene Name	FXYD6
Location	11q23.3

Bibliography

Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4

Kowarz E, Burmeister T, Lo Nigro L, Jansen MW, Delabesse E, Klingebiel T, Dingermann T, Meyer C, Marschalek R

MLL fusion allele Leukemia

PMID 17410185

Translocations implicated (Data extracted from papers in the Atlas)

	ins(4;11)(q21;q23q23) AFF1/FXYD6

External links

AFF1 (4q21.3) FXYD6 (11q23.3)

Mitelman database	ins(4;11)(q21;q23q23) [Case List]    ins(4;11)(q21;q23q23) [Transloc-MCList] AFF1/FXYD6 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jul 8 15:28:32 CEST 2019

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