| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 2513 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
| Genes involved and Proteins |
| Gene Name | AFF1 |
| Location | 4q21.3 |
| Gene Name | FXYD6 |
| Location | 11q23.3 |
| Bibliography |
| Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4 |
| Kowarz E, Burmeister T, Lo Nigro L, Jansen MW, Delabesse E, Klingebiel T, Dingermann T, Meyer C, Marschalek R |
| MLL fusion allele Leukemia |
| PMID 17410185 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| ins(4;11)(q21;q23q23) AFF1/FXYD6 | |
| External links |
| Mitelman database | ins(4;11)(q21;q23q23) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Sep 7 15:08:32 CEST 2020 |
For comments and suggestions or contributions, please contact us