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ins(10;11)(p12;q23q23) MLLT10/CLP1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2963
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute monoblastic leukemia (FAB type M5)

Genes involved and Proteins

Gene NameMLLT10
Location 10p12.31
Gene NameCLP1
Location 11q12.1

Bibliography

AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12)
Tanabe S, Bohlander SK, Vignon CV, Espinosa R 3rd, Zhao N, Strissel PL, Zeleznik-Le NJ, Rowley JD
Blood 1996 Nov 1;88(9):3535-45
PMID 8896421
 


Translocations implicated (Data extracted from papers in the Atlas)

 ins(10;11)(p12;q23q23) MLLT10/CLP1

External links

MLLT10 (10p12.31) CLP1 (11q12.1)

Mitelman databaseins(10;11)(p12;q23q23) [Case List]    ins(10;11)(p12;q23q23) [Transloc-MCList] MLLT10/CLP1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Nov 6 14:04:33 CET 2018


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