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ins(11;4)(q23;q21q31) ELF2/KMT2A

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2678

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameELF2
Location 4q31.1
Gene NameKMT2A
Location 11q23.3

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4
Kowarz E, Burmeister T, Lo Nigro L, Jansen MW, Delabesse E, Klingebiel T, Dingermann T, Meyer C, Marschalek R
MLL fusion allele Leukemia
PMID 17410185
 


Translocations implicated (Data extracted from papers in the Atlas)

 ins(11;4)(q23;q21q31) ELF2/KMT2A

External links

ELF2 (4q31.1) KMT2A (11q23.3)

Mitelman databaseins(11;4)(q23;q21q31) [Case List]    ins(11;4)(q23;q21q31) [Transloc-MCList] ELF2/KMT2A [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:22:47 CET 2018


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jlhuret@AtlasGeneticsOncology.org.