| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3160 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute myeloid leukemia, NOS |
| Genes involved and Proteins |
| Gene Name | RUNX1 |
| Location | 21q22.12 |
| Gene Name | CBFA2T2 |
| Location | 20q11.22 |
| Bibliography |
| CBFA2T2 and C20orf112: two novel fusion partners of RUNX1 in acute myeloid leukemia |
| Guastadisegni MC, Lonoce A, Impera L, Di Terlizzi F, Fugazza G, Aliano S, Grasso R, Cluzeau T, Raynaud S, Rocchi M, Storlazzi CT |
| Leukemia 2010 Aug;24(8):1516-9 |
| PMID 20520637 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| ins(21;20)(q22;q11q11) RUNX1/CBFA2T2 | |
| External links |
| Mitelman database | ins(21;20)(q22;q11q11) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Sep 7 15:08:33 CEST 2020 |
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