Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 3160 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Acute myeloid leukemia, NOS |
Genes involved and Proteins |
Gene Name | RUNX1 |
Location | 21q22.12 |
Gene Name | CBFA2T2 |
Location | 20q11.22 |
Bibliography |
CBFA2T2 and C20orf112: two novel fusion partners of RUNX1 in acute myeloid leukemia |
Guastadisegni MC, Lonoce A, Impera L, Di Terlizzi F, Fugazza G, Aliano S, Grasso R, Cluzeau T, Raynaud S, Rocchi M, Storlazzi CT |
Leukemia 2010 Aug;24(8):1516-9 |
PMID 20520637 |
Translocations implicated (Data extracted from papers in the Atlas) |
ins(21;20)(q22;q11q11) RUNX1/CBFA2T2 | |
External links |
Mitelman database | ins(21;20)(q22;q11q11) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:26:56 CET 2020 |
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