ins(21;20)(q22;q11q11) RUNX1/CBFA2T2

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3160
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute myeloid leukemia, NOS

Genes involved and Proteins

Gene Name	RUNX1
Location	21q22.12

Gene Name	CBFA2T2
Location	20q11.22

Bibliography

CBFA2T2 and C20orf112: two novel fusion partners of RUNX1 in acute myeloid leukemia

Guastadisegni MC, Lonoce A, Impera L, Di Terlizzi F, Fugazza G, Aliano S, Grasso R, Cluzeau T, Raynaud S, Rocchi M, Storlazzi CT

Leukemia 2010 Aug;24(8):1516-9

PMID 20520637

Translocations implicated (Data extracted from papers in the Atlas)

	ins(21;20)(q22;q11q11) RUNX1/CBFA2T2

External links

RUNX1 (21q22.12) CBFA2T2 (20q11.22)

Mitelman database	ins(21;20)(q22;q11q11) [Case List]    ins(21;20)(q22;q11q11) [Transloc-MCList] RUNX1/CBFA2T2 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:19:58 CET 2018

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