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ins(X;11)(q26;q23q23) KMT2A/CT45A2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2874
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Bilineage or biphenotypic leukemia

Genes involved and Proteins

Gene NameKMT2A
Location 11q23.3
Gene NameCT45A2
Location Xq26.3

Bibliography

A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia
Cerveira N, Meyer C, Santos J, Torres L, Lisboa S, Pinheiro M, Bizarro S, Correia C, Norton L, Marschalek R, Teixeira MR
BMC Cancer 2010 Sep 29;10:518
PMID 20920256
 


Translocations implicated (Data extracted from papers in the Atlas)

 ins(X;11)(q26;q23q23) KMT2A/CT45A2

External links

KMT2A (11q23.3) CT45A2 (Xq26.3)

Mitelman databaseins(X;11)(q26;q23q23) [Case List]    ins(X;11)(q26;q23q23) [Transloc-MCList] KMT2A/CT45A2 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:18:37 CEST 2018


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