ins(X;11)(q26;q23q23) KMT2A/CT45A2

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	2874
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Bilineage or biphenotypic leukemia

Genes involved and Proteins

Gene Name	KMT2A
Location	11q23.3

Gene Name	CT45A2
Location	Xq26.3

Bibliography

A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia

Cerveira N, Meyer C, Santos J, Torres L, Lisboa S, Pinheiro M, Bizarro S, Correia C, Norton L, Marschalek R, Teixeira MR

BMC Cancer 2010 Sep 29;10:518

PMID 20920256

Translocations implicated (Data extracted from papers in the Atlas)

	ins(X;11)(q26;q23q23) KMT2A/CT45A2

External links

KMT2A (11q23.3) CT45A2 (Xq26.3)

Mitelman database	ins(X;11)(q26;q23q23) [Case List]    ins(X;11)(q26;q23q23) [Transloc-MCList] KMT2A/CT45A2 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Nov 6 14:04:35 CET 2018

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