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inv(14)(q11q32) BCL11B/TRD

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2538
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameBCL11B
Location 14q32.2
Gene NameTRD
Location 10p13

Bibliography

Disruption of the BCL11B gene through inv(14)(q11
Przybylski GK, Dik WA, Wanzeck J, Grabarczyk P, Majunke S, Martin-Subero JI, Siebert R, Dölken G, Ludwig WD, Verhaaf B, van Dongen JJ, Schmidt CA, Langerak AW
2q32 31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL
PMID 15668700
 


Translocations implicated (Data extracted from papers in the Atlas)

 inv(14)(q11q32) BCL11B/TRD

External links

BCL11B (14q32.2) TRD (10p13)

Mitelman databaseinv(14)(q11q32) [Case List]    inv(14)(q11q32) [Transloc-MCList] BCL11B/TRD [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon Jul 9 10:12:57 CEST 2018


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