t(1;5)(q21;q32) TPM3/PDGFRB

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	1455
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Chronic eosinophilic leukemia/hypereosinophilic syndrome

Genes involved and Proteins

Gene Name	TPM3
Location	1q21.3

Gene Name	PDGFRB
Location	5q32

Bibliography

TPM3/PDGFRB fusion transcript and its reciprocal in chronic eosinophilic leukemia

Rosati R, La Starza R, Luciano L, Gorello P, Matteucci C, Pierini V, Romoli S, Crescenzi B, Rotoli B, Martelli MF, Pane F, Mecucci C

Leukemia 2006 Sep;20(9):1623-4

PMID 16838028

Translocations implicated (Data extracted from papers in the Atlas)

	t(1;5)(q21;q32) TPM3/PDGFRB

External links

TPM3 (1q21.3) PDGFRB (5q32)

Mitelman database	t(1;5)(q21;q32) [Case List]    t(1;5)(q21;q32) [Transloc-MCList] TPM3/PDGFRB [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:20:12 CET 2018

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