| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 1455 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Chronic eosinophilic leukemia/hypereosinophilic syndrome |
| Genes involved and Proteins |
| Gene Name | TPM3 |
| Location | 1q21.3 |
| Gene Name | PDGFRB |
| Location | 5q32 |
| Bibliography |
| TPM3/PDGFRB fusion transcript and its reciprocal in chronic eosinophilic leukemia |
| Rosati R, La Starza R, Luciano L, Gorello P, Matteucci C, Pierini V, Romoli S, Crescenzi B, Rotoli B, Martelli MF, Pane F, Mecucci C |
| Leukemia 2006 Sep;20(9):1623-4 |
| PMID 16838028 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(1;5)(q21;q32) TPM3/PDGFRB | |
| External links |
| Mitelman database | t(1;5)(q21;q32) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:27:04 CET 2020 |
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