Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(1;5)(q21;q32) TPM3/PDGFRB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 1455
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic eosinophilic leukemia/hypereosinophilic syndrome

Genes involved and Proteins

Gene NameTPM3
Location 1q21.3
Gene NamePDGFRB
Location 5q32

Bibliography

TPM3/PDGFRB fusion transcript and its reciprocal in chronic eosinophilic leukemia
Rosati R, La Starza R, Luciano L, Gorello P, Matteucci C, Pierini V, Romoli S, Crescenzi B, Rotoli B, Martelli MF, Pane F, Mecucci C
Leukemia 2006 Sep;20(9):1623-4
PMID 16838028
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;5)(q21;q32) TPM3/PDGFRB

External links

TPM3 (1q21.3) PDGFRB (5q32)

Mitelman databaset(1;5)(q21;q32) [Case List]    t(1;5)(q21;q32) [Transloc-MCList] TPM3/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 28 18:18:51 CEST 2018


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.