Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 1455 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Chronic eosinophilic leukemia/hypereosinophilic syndrome |
Genes involved and Proteins |
Gene Name | TPM3 |
Location | 1q21.3 |
Gene Name | PDGFRB |
Location | 5q32 |
Bibliography |
TPM3/PDGFRB fusion transcript and its reciprocal in chronic eosinophilic leukemia |
Rosati R, La Starza R, Luciano L, Gorello P, Matteucci C, Pierini V, Romoli S, Crescenzi B, Rotoli B, Martelli MF, Pane F, Mecucci C |
Leukemia 2006 Sep;20(9):1623-4 |
PMID 16838028 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(1;5)(q21;q32) TPM3/PDGFRB | |
External links |
Mitelman database | t(1;5)(q21;q32) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:27:04 CET 2020 |
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