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t(1;5)(q21;q32) PDE4DIP/PDGFRB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3381
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Myelodysplastic/myeloproliferative disease, NOS

Genes involved and Proteins

Gene NamePDE4DIP
Location 1q21.2
Gene NamePDGFRB
Location 5q32

Bibliography

Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib
Wilkinson K, Velloso ER, Lopes LF, Lee C, Aster JC, Shipp MA, Aguiar RC
Blood 2003 Dec 1;102(12):4187-90
PMID 12907457
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;5)(q21;q32) PDE4DIP/PDGFRB

External links

PDE4DIP (1q21.2) PDGFRB (5q32)

Mitelman databaset(1;5)(q21;q32) [Case List]    t(1;5)(q21;q32) [Transloc-MCList] PDE4DIP/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Aug 28 18:18:51 CEST 2018


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jlhuret@AtlasGeneticsOncology.org.