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t(1;7)(p35;q34) TRB/LCK

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3382
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NameTRB
Gene NameLCK
Location 1p35.2

Bibliography

The LCK gene is involved in the t(1;7)(p34;q34) in the T-cell acute lymphoblastic leukemia derived cell line, HSB-2
Burnett RC, David JC, Harden AM, Le Beau MM, Rowley JD, Diaz MO
Genes Chromosomes Cancer 1991 Nov;3(6):461-7
PMID 1663780
 
Chromosomal translocations joining LCK and TCRB loci in human T cell leukemia
Tycko B, Smith SD, Sklar J
J Exp Med 1991 Oct 1;174(4):867-73
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;7)(p35;q34) TRB/LCK

External links

TRB () LCK (1p35.2)

Mitelman databaset(1;7)(p35;q34) [Case List]    t(1;7)(p35;q34) [Transloc-MCList] TRB/LCK [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon Jul 9 10:13:06 CEST 2018


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