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t(1;8)(q31;p11) TPR/FGFR1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3273

Clinics and Pathology

Disease Chronic myeloproliferative disorder, NOS

Genes involved and Proteins

Gene NameTPR
Location 3p26.1
Gene NameFGFR1
Location 8p11.23

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome
Li F, Zhai YP, Tang YM, Wang LP, Wan PJ
Genes Chromosomes Cancer 2012 Sep;51(9):890-7
PMID 22619110
 
Molecular identification of a TPR-FGFR1 fusion transcript in an adult with myeloproliferative neoplasm, T-lymphoblastic lymphoma, and a t(1;8)(q25;p11
Kim SY, Kim JE, Park S, Kim HK
2) Cancer Genet
PMID 25037443
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;8)(q31;p11) TPR/FGFR1

External links

TPR (3p26.1) FGFR1 (8p11.23)

Mitelman databaset(1;8)(q31;p11) [Case List]    t(1;8)(q31;p11) [Transloc-MCList] TPR/FGFR1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:20:40 CET 2018


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