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t(1;11)(q24;p15) NUP98/PRRX1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 3383
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloblastic leukemia with maturation (FAB type M2)|Acute myeloid leukemia, NOS|Chronic myeloid leukemia, t(9;22)

Genes involved and Proteins

Gene NameNUP98
Location 11p15.4
Gene NamePRRX1
Location 1q24.2


NUP98 is fused to PMX1 homeobox gene in human acute myelogenous leukemia with chromosome translocation t(1;11)(q23;p15)
Nakamura T, Yamazaki Y, Hatano Y, Miura I
Blood 1999 Jul 15;94(2):741-7
PMID 10397741
Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal rearrangements
Kobzev YN, Martinez-Climent J, Lee S, Chen J, Rowley JD
Genes Chromosomes Cancer 2004 Dec;41(4):339-52
PMID 15390187

Translocations implicated (Data extracted from papers in the Atlas)

 t(1;11)(q24;p15) NUP98/PRRX1

External links

NUP98 (11p15.4) PRRX1 (1q24.2)

Mitelman databaset(1;11)(q24;p15) [Case List]    t(1;11)(q24;p15) [Transloc-MCList] NUP98/PRRX1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Tue Mar 12 13:12:57 CET 2019

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