| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3297 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
| Genes involved and Proteins |
| Gene Name | TRD |
| Location | 14q11.2 |
| Gene Name | TAL1 |
| Location | 1p33 |
| Bibliography |
| Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T-cell leukemias |
| Bernard O, Guglielmi P, Jonveaux P, Cherif D, Gisselbrecht S, Mauchauffe M, Berger R, Larsen CJ, Mathieu-Mahul D |
| Genes Chromosomes Cancer 1990 Jan;1(3):194-208 |
| PMID 1964581 |
| The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein |
| Chen Q, Cheng JT, Tasi LH, Schneider N, Buchanan G, Carroll A, Crist W, Ozanne B, Siciliano MJ, Baer R |
| EMBO J 1990 Feb;9(2):415-24 |
| PMID 2303035 |
| Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma |
| Finger LR, Kagan J, Christopher G, Kurtzberg J, Hershfield MS, Nowell PC, Croce CM |
| Proc Natl Acad Sci U S A 1989 Jul;86(13):5039-43 |
| PMID 2740341 |
| Characterization of translocation t(1;14)(p32;q11) in a T and in a B acute leukemia |
| Bernard O, Barin C, Charrin C, Mathieu-Mahul D, Berger R |
| Leukemia 1993 Oct;7(10):1509-13 |
| PMID 8412312 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(1;14)(p33;q11) TRD/TAL1 | |
| External links |
| Mitelman database | t(1;14)(p33;q11) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:27:10 CET 2020 |
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