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t(2;2)(p23;p23) YPEL5/PPP1CB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3339

Clinics and Pathology

Disease Chronic lymphocytic leukemia

Genes involved and Proteins

Gene NameYPEL5
Location 2p23.1
Gene NamePPP1CB
Location 2p23.2

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia
Velusamy T, Palanisamy N, Kalyana-Sundaram S, Sahasrabuddhe AA, Maher CA, Robinson DR, Bahler DW, Cornell TT, Wilson TE, Lim MS, Chinnaiyan AM, Elenitoba-Johnson KS
Proc Natl Acad Sci U S A 2013 Feb 19;110(8):3035-40
PMID 23382248
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;2)(p23;p23) YPEL5/PPP1CB

External links

YPEL5 (2p23.1) PPP1CB (2p23.2)

Mitelman databaset(2;2)(p23;p23) [Case List]    t(2;2)(p23;p23) [Transloc-MCList] YPEL5/PPP1CB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:20:51 CET 2018


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jlhuret@AtlasGeneticsOncology.org.