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t(2;3)(p11;q27) IGK/BCL6

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2817

Clinics and Pathology

Disease Follicular lymphoma:Mature B-cell neoplasm, NOS

Genes involved and Proteins

Gene NameIGK
Location 2p11.2
Gene NameBCL6
Location 3q27.3

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization
Sanchez-Izquierdo D, Siebert R, Harder L, Marugan I, Gozzetti A, Price HP, Gesk S, Hernandez-Rivas JM, Benet I, Solé F, Sonoki T, Le Beau MM, Schlegelberger B, Dyer MJ, Garcia-Conde J, Martinez-Climent JA
Leukemia 2001 Sep;15(9):1475-84
PMID 11516111
 
A novel t(2;3)(p11;q27) in a case of follicular lymphoma
Tapinassi C, Micucci C, Lahortiga I, Malazzi O, Gasparini P, Gorosquieta A, Odero MD, Belloni E
Cancer Genet Cytogenet 2007 Jan 1;172(1):70-3
PMID 17175383
 
Variant translocation of the BCL6 gene to immunoglobulin kappa light chain gene in B-cell lymphoma
Suzuki K, Miki T, Kawamata N, Hirosawa S, Yoshizawa K, Kiyosawa K, Aoki N
Jpn J Cancer Res 1994 Sep;85(9):911-7
PMID 7961119
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;3)(p11;q27) IGK/BCL6

External links

IGK (2p11.2) BCL6 (3q27.3)

Mitelman databaset(2;3)(p11;q27) [Case List]    t(2;3)(p11;q27) [Transloc-MCList] IGK/BCL6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:20:52 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.