Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 3189 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Diffuse large B-cell lymphoma |
Genes involved and Proteins |
Gene Name | SEC31A |
Location | 4q21.22 |
Gene Name | ALK |
Location | 2p23.2 |
Bibliography |
ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions |
Van Roosbroeck K, Cools J, Dierickx D, Thomas J, Vandenberghe P, Stul M, Delabie J, De Wolf-Peeters C, Marynen P, Wlodarska I |
Haematologica 2010 Mar;95(3):509-13 |
PMID 20207848 |
Cytogenetically complex SEC31A-ALK fusions are recurrent in ALK-positive large B-cell lymphomas |
Bedwell C, Rowe D, Moulton D, Jones G, Bown N, Bacon CM |
Haematologica 2011 Feb;96(2):343-6 |
PMID 21109691 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(2;4)(p23;q21) SEC31A/ALK | |
External links |
Mitelman database | t(2;4)(p23;q21) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:27:16 CET 2020 |
For comments and suggestions or contributions, please contact us