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t(2;5)(p16;q32) SPTBN1/PDGFRB

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3389
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic myeloproliferative disorder, NOS

Genes involved and Proteins

Gene NameSPTBN1
Location 2p16.2
Gene NamePDGFRB
Location 5q32

Bibliography

Fusion of PRKG2 and SPTBN1 to the platelet-derived growth factor receptor beta gene (PDGFRB) in imatinib-responsive atypical myeloproliferative disorders
Gallagher G, Horsman DE, Tsang P, Forrest DL
Cancer Genet Cytogenet 2008 Feb;181(1):46-51
PMID 18262053
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;5)(p16;q32) SPTBN1/PDGFRB

External links

SPTBN1 (2p16.2) PDGFRB (5q32)

Mitelman databaset(2;5)(p16;q32) [Case List]    t(2;5)(p16;q32) [Transloc-MCList] SPTBN1/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Tue Aug 28 18:19:12 CEST 2018


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