t(2;10)(p15;p12) XPO1/MLLT10

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3334
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene Name	XPO1
Location	2p15

Gene Name	MLLT10
Location	10p12.31

Bibliography

Cryptic XPO1-MLLT10 translocation is associated with HOXA locus deregulation in T-ALL

Bond J, Bergon A, Durand A, Tigaud I, Thomas X, Asnafi V, Spicuglia S, Macintyre E

Blood 2014 Nov 6;124(19):3023-5

PMID 25377562

Translocations implicated (Data extracted from papers in the Atlas)

	t(2;10)(p15;p12) XPO1/MLLT10

External links

XPO1 (2p15) MLLT10 (10p12.31)

Mitelman database	t(2;10)(p15;p12) [Case List]    t(2;10)(p15;p12) [Transloc-MCList] XPO1/MLLT10 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 13 22:15:41 CET 2019

For comments and suggestions or contributions, please contact us