Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 3334 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
Genes involved and Proteins |
Gene Name | XPO1 |
Location | 2p15 |
Gene Name | MLLT10 |
Location | 10p12.31 |
Bibliography |
Cryptic XPO1-MLLT10 translocation is associated with HOXA locus deregulation in T-ALL |
Bond J, Bergon A, Durand A, Tigaud I, Thomas X, Asnafi V, Spicuglia S, Macintyre E |
Blood 2014 Nov 6;124(19):3023-5 |
PMID 25377562 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(2;10)(p15;p12) XPO1/MLLT10 | |
External links |
Mitelman database | t(2;10)(p15;p12) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:27:19 CET 2020 |
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