| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 3334 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Acute lymphoblastic leukemia/lymphoblastic lymphoma |
| Genes involved and Proteins |
| Gene Name | XPO1 |
| Location | 2p15 |
| Gene Name | MLLT10 |
| Location | 10p12.31 |
| Bibliography |
| Cryptic XPO1-MLLT10 translocation is associated with HOXA locus deregulation in T-ALL |
| Bond J, Bergon A, Durand A, Tigaud I, Thomas X, Asnafi V, Spicuglia S, Macintyre E |
| Blood 2014 Nov 6;124(19):3023-5 |
| PMID 25377562 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(2;10)(p15;p12) XPO1/MLLT10 | |
| External links |
| Mitelman database | t(2;10)(p15;p12) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Sep 7 15:08:54 CEST 2020 |
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