| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 1663 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Adult T-cell lymphoma/leukemia (HTLV-1+) |
| Genes involved and Proteins |
| Gene Name | EPC1 |
| Location | 10p11.22 |
| Gene Name | ASXL2 |
| Location | 2p23.3 |
| Bibliography |
| Alteration of enhancer of polycomb 1 at 10p11 |
| Nakahata S, Saito Y, Hamasaki M, Hidaka T, Arai Y, Taki T, Taniwaki M, Morishita K |
| 2 is one of the genetic events leading to development of adult T-cell leukemia/lymphoma Genes Chromosomes Cancer |
| PMID 19484761 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(2;10)(p23;p11) EPC1/ASXL2 | |
| External links |
| Mitelman database | t(2;10)(p23;p11) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:27:19 CET 2020 |
For comments and suggestions or contributions, please contact us