Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 1663 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Adult T-cell lymphoma/leukemia (HTLV-1+) |
Genes involved and Proteins |
Gene Name | EPC1 |
Location | 10p11.22 |
Gene Name | ASXL2 |
Location | 2p23.3 |
Bibliography |
Alteration of enhancer of polycomb 1 at 10p11 |
Nakahata S, Saito Y, Hamasaki M, Hidaka T, Arai Y, Taki T, Taniwaki M, Morishita K |
2 is one of the genetic events leading to development of adult T-cell leukemia/lymphoma Genes Chromosomes Cancer |
PMID 19484761 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(2;10)(p23;p11) EPC1/ASXL2 | |
External links |
Mitelman database | t(2;10)(p23;p11) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:27:19 CET 2020 |
For comments and suggestions or contributions, please contact us