t(2;10)(p23;p11) EPC1/ASXL2

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	1663
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Adult T-cell lymphoma/leukemia (HTLV-1+)

Genes involved and Proteins

Gene Name	EPC1
Location	10p11.22

Gene Name	ASXL2
Location	2p23.3

Bibliography

Alteration of enhancer of polycomb 1 at 10p11

Nakahata S, Saito Y, Hamasaki M, Hidaka T, Arai Y, Taki T, Taniwaki M, Morishita K

2 is one of the genetic events leading to development of adult T-cell leukemia/lymphoma Genes Chromosomes Cancer

PMID 19484761

Translocations implicated (Data extracted from papers in the Atlas)

	t(2;10)(p23;p11) EPC1/ASXL2

External links

EPC1 (10p11.22) ASXL2 (2p23.3)

Mitelman database	t(2;10)(p23;p11) [Case List]    t(2;10)(p23;p11) [Transloc-MCList] EPC1/ASXL2 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jan 27 15:18:12 CET 2020

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