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t(2;11)(q22;q21) CXCR4/MAML2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2643
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic lymphocytic leukemia

Genes involved and Proteins

Gene NameCXCR4
Location 2q22.1
Gene NameMAML2

Bibliography

Translocation t(2;11) in CLL cells results in CXCR4/MAML2 fusion oncogene
Acunzo M, Romano G, Wernicke D, Balatti V, Rassenti LZ, dell'Aquila M, Kipps TJ, Pekarsky Y, Croce CM
Blood 2014 Jul 10;124(2):259-62
PMID 24855209
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;11)(q22;q21) CXCR4/MAML2

External links

CXCR4 (2q22.1) MAML2 ()

Mitelman databaset(2;11)(q22;q21) [Case List]    t(2;11)(q22;q21) [Transloc-MCList] CXCR4/MAML2 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon May 14 13:42:10 CEST 2018


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