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t(2;11)(q22;q21) CXCR4/MAML2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2643
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic lymphocytic leukemia

Genes involved and Proteins

Gene NameCXCR4
Location 2q22.1
Gene NameMAML2
Location 11q21

Bibliography

Translocation t(2;11) in CLL cells results in CXCR4/MAML2 fusion oncogene
Acunzo M, Romano G, Wernicke D, Balatti V, Rassenti LZ, dell'Aquila M, Kipps TJ, Pekarsky Y, Croce CM
Blood 2014 Jul 10;124(2):259-62
PMID 24855209
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;11)(q22;q21) CXCR4/MAML2

External links

CXCR4 (2q22.1) MAML2 (11q21)

Mitelman databaset(2;11)(q22;q21) [Case List]    t(2;11)(q22;q21) [Transloc-MCList] CXCR4/MAML2 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:19:19 CEST 2018


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