t(2;14)(p24;q32) IGH/MYCN

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	2805
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Mantle cell lymphoma

Genes involved and Proteins

Gene Name	IGH
Location	14q32.33

Gene Name	MYCN
Location	2p24.3

Bibliography

Translocations targeting CCND2, CCND3, and MYCN do occur in t(11;14)-negative mantle cell lymphomas

Wlodarska I, Dierickx D, Vanhentenrijk V, Van Roosbroeck K, Pospísilová H, Minnei F, Verhoef G, Thomas J, Vandenberghe P, De Wolf-Peeters C

Blood 2008 Jun 15;111(12):5683-90

PMID 18391076

Translocations implicated (Data extracted from papers in the Atlas)

	t(2;14)(p24;q32) IGH/MYCN

External links

IGH (14q32.33) MYCN (2p24.3)

Mitelman database	t(2;14)(p24;q32) [Case List]    t(2;14)(p24;q32) [Transloc-MCList] IGH/MYCN [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Feb 19 18:21:32 CET 2020

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