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t(2;14)(p24;q32) IGH/MYCN

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2805
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Mantle cell lymphoma

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NameMYCN
Location 2p24.3

Bibliography

Translocations targeting CCND2, CCND3, and MYCN do occur in t(11;14)-negative mantle cell lymphomas
Wlodarska I, Dierickx D, Vanhentenrijk V, Van Roosbroeck K, Pospísilová H, Minnei F, Verhoef G, Thomas J, Vandenberghe P, De Wolf-Peeters C
Blood 2008 Jun 15;111(12):5683-90
PMID 18391076
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;14)(p24;q32) IGH/MYCN

External links

IGH (14q32.33) MYCN (2p24.3)

Mitelman databaset(2;14)(p24;q32) [Case List]    t(2;14)(p24;q32) [Transloc-MCList] IGH/MYCN [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:19:22 CEST 2018


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jlhuret@AtlasGeneticsOncology.org.