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t(2;14)(p24;q32) IGH/MYCN

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2805

Clinics and Pathology

Disease Mantle cell lymphoma

Genes involved and Proteins

Gene NameIGH
Location 14q32.33
Gene NameMYCN
Location 2p24.3

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

Translocations targeting CCND2, CCND3, and MYCN do occur in t(11;14)-negative mantle cell lymphomas
Wlodarska I, Dierickx D, Vanhentenrijk V, Van Roosbroeck K, Pospísilová H, Minnei F, Verhoef G, Thomas J, Vandenberghe P, De Wolf-Peeters C
Blood 2008 Jun 15;111(12):5683-90
PMID 18391076
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;14)(p24;q32) IGH/MYCN

External links

IGH (14q32.33) MYCN (2p24.3)

Mitelman databaset(2;14)(p24;q32) [Case List]    t(2;14)(p24;q32) [Transloc-MCList] IGH/MYCN [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:23:17 CET 2018


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jlhuret@AtlasGeneticsOncology.org.