t(2;14)(q22;q32) ZEB2/BCL11B

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3347
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute myeloid leukemia, NOS

Genes involved and Proteins

Gene Name	ZEB2
Location	2q22.3

Gene Name	BCL11B
Location	14q32.2

Bibliography

Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)

Torkildsen S, Gorunova L, Beiske K, Tjønnfjord GE, Heim S, Panagopoulos I

PLoS One 2015 Jul 17;10(7):e0132736

PMID 26186352

Translocations implicated (Data extracted from papers in the Atlas)

	t(2;14)(q22;q32) ZEB2/BCL11B

External links

ZEB2 (2q22.3) BCL11B (14q32.2)

Mitelman database	t(2;14)(q22;q32) [Case List]    t(2;14)(q22;q32) [Transloc-MCList] ZEB2/BCL11B [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon May 11 15:53:22 CEST 2020

For comments and suggestions or contributions, please contact us