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t(2;14)(q22;q32) ZEB2/BCL11B

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3347
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myeloid leukemia, NOS

Genes involved and Proteins

Gene NameZEB2
Location 2q22.3
Gene NameBCL11B
Location 14q32.2

Bibliography

Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)
Torkildsen S, Gorunova L, Beiske K, Tjønnfjord GE, Heim S, Panagopoulos I
PLoS One 2015 Jul 17;10(7):e0132736
PMID 26186352
 

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;14)(q22;q32) ZEB2/BCL11B

External links

ZEB2 (2q22.3) BCL11B (14q32.2)

Mitelman databaset(2;14)(q22;q32) [Case List]    t(2;14)(q22;q32) [Transloc-MCList] ZEB2/BCL11B [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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indexed on : Tue Aug 28 18:19:23 CEST 2018

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