Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(2;22)(p16;q11) IGL::REL

(Note : for Links provided by Atlas : click)


Atlas_Id 2831
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Follicular lymphoma|Hodgkin disease, NOS

Genes involved and Proteins

Gene NameIGL
Location 22q11.22
Gene NameREL
Location 2p16.1


Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci
Martín-Subero JI, Harder L, Gesk S, Schlegelberger B, Grote W, Martinez-Climent JA, Dyer MJ, Novo FJ, Calasanz MJ, Siebert R
Int J Cancer 2002 Mar 20;98(3):470-4
PMID 11920602
Chromosomal breakpoints affecting immunoglobulin loci are recurrent in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
Martín-Subero JI, Klapper W, Sotnikova A, Callet-Bauchu E, Harder L, Bastard C, Schmitz R, Grohmann S, Höppner J, Riemke J, Barth TF, Berger F, Bernd HW, Claviez A, Gesk S, Frank GA, Kaplanskaya IB, Möller P, Parwaresch RM, Rüdiger T, Stein H, Küppers R, Hansmann ML, Siebert R; Deutsche Krebshilfe Network Project Molecular Mechanisms in Malignant Lymphomas
Cancer Res 2006 Nov 1;66(21):10332-8
PMID 17079453

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;22)(p16;q11) IGL/REL

External links

IGL (22q11.22) REL (2p16.1)

Mitelman databaset(2;22)(p16;q11)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Fri Oct 8 16:38:10 CEST 2021

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