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t(2;22)(p16;q11) IGL/REL

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2831
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Follicular lymphoma|Hodgkin disease, NOS

Genes involved and Proteins

Gene NameIGL
Location 19q13.41
Gene NameREL
Location 1q32.1

Bibliography

Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci
Martín-Subero JI, Harder L, Gesk S, Schlegelberger B, Grote W, Martinez-Climent JA, Dyer MJ, Novo FJ, Calasanz MJ, Siebert R
Int J Cancer 2002 Mar 20;98(3):470-4
PMID 11920602
 
Chromosomal breakpoints affecting immunoglobulin loci are recurrent in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
Martín-Subero JI, Klapper W, Sotnikova A, Callet-Bauchu E, Harder L, Bastard C, Schmitz R, Grohmann S, Höppner J, Riemke J, Barth TF, Berger F, Bernd HW, Claviez A, Gesk S, Frank GA, Kaplanskaya IB, Möller P, Parwaresch RM, Rüdiger T, Stein H, Küppers R, Hansmann ML, Siebert R; Deutsche Krebshilfe Network Project Molecular Mechanisms in Malignant Lymphomas
Cancer Res 2006 Nov 1;66(21):10332-8
PMID 17079453
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;22)(p16;q11) IGL/REL

External links

IGL (19q13.41) REL (1q32.1)

Mitelman databaset(2;22)(p16;q11) [Case List]    t(2;22)(p16;q11) [Transloc-MCList] IGL/REL [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon May 14 13:42:16 CEST 2018


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