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t(2;22)(p23;q12) MYH9/ALK

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3396
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Anaplastic large cell lymphoma, systemic type

Genes involved and Proteins

Gene NameMYH9
Location 22q12.3
Gene NameALK
Location 2p23.2-p23.1

Bibliography

Non-muscle myosin heavy chain (MYH9): a new partner fused to ALK in anaplastic large cell lymphoma
Lamant L, Gascoyne RD, Duplantier MM, Armstrong F, Raghab A, Chhanabhai M, Rajcan-Separovic E, Raghab J, Delsol G, Espinos E
Genes Chromosomes Cancer 2003 Aug;37(4):427-32
PMID 12800156
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;22)(p23;q12) MYH9/ALK

External links

MYH9 (22q12.3) ALK (2p23.2-p23.1)

Mitelman databaset(2;22)(p23;q12) [Case List]    t(2;22)(p23;q12) [Transloc-MCList] MYH9/ALK [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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indexed on : Mon Jul 9 10:13:32 CEST 2018


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jlhuret@AtlasGeneticsOncology.org.