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t(3;9)(p13;p13) PAX5/FOXP1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3405
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes involved and Proteins

Gene NamePAX5
Location 9p13.2
Gene NameFOXP1
Location 3p13

Bibliography

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR
Nature 2007 Apr 12;446(7137):758-64
PMID 17344859
 
Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray
Kawamata N, Ogawa S, Zimmermann M, Niebuhr B, Stocking C, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Bartram CR, Koeffler HP
Proc Natl Acad Sci U S A 2008 Aug 19;105(33):11921-6
PMID 18697940
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(3;9)(p13;p13) PAX5/FOXP1

External links

PAX5 (9p13.2) FOXP1 (3p13)

Mitelman databaset(3;9)(p13;p13) [Case List]    t(3;9)(p13;p13) [Transloc-MCList] PAX5/FOXP1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Tue Aug 28 18:19:36 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.